Organophosphates

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15 Diseases Researched for Organophosphates

Name	AC	CK
Hypothyroidism	3	22
Thyroid Diseases	2	20
Pesticide-Induced Toxicity: Organophosphates	4	16
Pesticide Toxicity	3	14
Hyperthyroidism	1	10
Inappropriate TSH Secretion Syndrome	1	10
Psychological Distress	1	10
Suicidal Behavior	1	10
Suicidal Ideation	1	10
Allergies	1	2
Autoimmune Diseases	1	2
Chemically-Induced Liver Damage	1	2
Infertility: Male	1	2
Lead Poisoning	1	2
Sperm Quality: Low	1	2

5 Adverse Pharmacological Actions Researched for Organophosphates

Name	AC	CK
Endocrine Disruptor	1	10
Neurotoxic	1	10
Allergenic	1	2
Hepatotoxic	1	2
Oxidant	1	2

Research Articles 8
Cumulative Knowledge Score 12
Overall Research Rating GOOD

View the Evidence:
11 Abstracts with Organophosphates Research

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Organophosphate pesticide exposure has been associated with thyroid hormone changes in human subjects.Feb 15, 2010

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Pubmed Data : Toxicol Appl Pharmacol. 2010 Feb 15;243(1):19-26. Epub 2009 Nov 13. PMID: 19914268

Article Published Date : Feb 15, 2010

Study Type : Human Study

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Diseases : Hyperthyroidism, Hypothyroidism, Thyroid Diseases

Problem Substances : Organophosphates

[+]

Organophosphate pesticide exposure may adversely effect the thyroid. Aug 05, 2010

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Pubmed Data : Toxicol Appl Pharmacol. 2010 Aug 5. Epub 2010 Aug 5. PMID: 20691716

Article Published Date : Aug 05, 2010

Study Type : Human Study

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Diseases : Hypothyroidism, Inappropriate TSH Secretion Syndrome, Thyroid Diseases

Problem Substances : Organophosphates, Pesticides

Adverse Pharmacological Actions : Endocrine Disruptor

[+]

Pesticide exposure is associated with psychological distress and suicidal ideation. Nov 01, 2010

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Pubmed Data : Occup Environ Med. 2010 Nov;67(11):778-84. Epub 2010 Aug 25. PMID: 20798019

Article Published Date : Nov 01, 2010

Study Type : Human Study

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Diseases : Pesticide-Induced Toxicity: Organophosphates, Pesticide Toxicity , Psychological Distress, Suicidal Behavior, Suicidal Ideation

Problem Substances : Organochlorine pesticides, Organophosphates, Pesticides

Adverse Pharmacological Actions : Neurotoxic

[+]

Celery extract protects against pesticide-induced toxicity. Nov 01, 2011

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Pubmed Data : Hum Exp Toxicol. 2011 Nov 1. Epub 2011 Nov 1. PMID: 22045891

Article Published Date : Nov 01, 2011

Study Type : Animal Study

Additional Links

Substances : Celery, Flavonoids

Diseases : Chemically-Induced Liver Damage, Pesticide-Induced Toxicity: Organophosphates, Pesticide Toxicity

Pharmacological Actions : Hepatoprotective

Problem Substances : Dichlorvos, Organophosphates, Pesticides

Adverse Pharmacological Actions : Hepatotoxic, Oxidant

[+]

Crocin reduced the toxic effects of diazinon by inhibiting apoptosis in aortic tissue.Jun 30, 2016

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Pubmed Data : Toxicol Ind Health. 2016 Jul ;32(7):1237-45. Epub 2014 Nov 20. PMID: 27353299

Article Published Date : Jun 30, 2016

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Pesticide-Induced Toxicity: Organophosphates

Pharmacological Actions : Anti-Apoptotic, Cytoprotective

Problem Substances : Organophosphates

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Huperzine A has protective effects against glutamatergic systems disorder caused by Isocarbophos poisoning.Apr 30, 2013

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Pubmed Data : Wei Sheng Yan Jiu. 2013 May ;42(3):419-23. PMID: 23805518

Article Published Date : Apr 30, 2013

Study Type : Animal Study

Additional Links

Substances : Huperzine

Diseases : Pesticide-Induced Toxicity: Organophosphates

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Organophosphates

[+]

Nigella sativa could be efficacious against organophosphate induced oxidative damage.Jun 29, 2018

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Pubmed Data : Niger J Physiol Sci. 2018 Jun 30 ;33(1):83-88. Epub 2018 Jun 30. PMID: 30091737

Article Published Date : Jun 29, 2018

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : Brain: Oxidative Stress, Lipid Peroxidation

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Problem Substances : Dichlorvos, Organophosphates

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Prior exposure to organophosphorus and organochlorine pesticides increases the allergic potential of environmental chemical allergens.Oct 21, 2010

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Pubmed Data : Toxicol Lett. 2010 Oct 21. Epub 2010 Oct 21. PMID: 20920556

Article Published Date : Oct 21, 2010

Study Type : Animal Study

Additional Links

Diseases : Allergies, Autoimmune Diseases, Pesticide Toxicity

Problem Substances : Organochlorine compounds, Organochlorine pesticides, Organophosphates, Pesticides

Adverse Pharmacological Actions : Allergenic

[+]

The administration of vitamin B complex (in combination with a steroid) early before clinical signs of organophosphates exposure are manifest is effective in alleviating neuropathy.Aug 31, 2004

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Pubmed Data : J Occup Health. 2004 Sep ;46(5):359-64. PMID: 15492452

Article Published Date : Aug 31, 2004

Study Type : Animal Study

Additional Links

Substances : Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin B-12, Vitamin B-6

Diseases : Aerotoxic Syndrome, Neurodegenerative Diseases, Neuropathies

Pharmacological Actions : Neuroprotective Agents

Anti Therapeutic Actions : Air Travel

Problem Substances : Organophosphates, Tricresyl phosphates (TCPs)

Adverse Pharmacological Actions : Neurotoxic

[+]

The insecticides dimethoate and deltamethrin have an adverse effect on the reproductive system of male mice.Jun 01, 2010

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Pubmed Data : Andrologia. 2010 Jun;42(3):182-6. PMID: 20500747

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Infertility: Male, Sperm Quality: Low

Problem Substances : Deltamethrin, Dimethoate, Organophosphates, Pyrethroid insecticide

[+]

Vitamin C ameliorates alterations in thyroid hormones concentrations induced by subchronic coadministration of chlorpyrifos and lead in wistar rats.Jan 01, 2011

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Pubmed Data : J Thyroid Res. 2011;2011:214924. Epub 2011 May 23. PMID: 21687644

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Hypothyroidism, Lead Poisoning, Pesticide-Induced Toxicity: Organophosphates

Problem Substances : Chlorpyrifos, Lead, Organophosphates, Pesticides

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Focus Your Research

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View the Evidence: 11 Abstracts with Organophosphates Research

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Organophosphate pesticide exposure has been associated with thyroid hormone changes in human subjects.Feb 15, 2010

Organophosphate pesticide exposure may adversely effect the thyroid. Aug 05, 2010

Pesticide exposure is associated with psychological distress and suicidal ideation. Nov 01, 2010

Celery extract protects against pesticide-induced toxicity. Nov 01, 2011

Crocin reduced the toxic effects of diazinon by inhibiting apoptosis in aortic tissue.Jun 30, 2016

Huperzine A has protective effects against glutamatergic systems disorder caused by Isocarbophos poisoning.Apr 30, 2013

Nigella sativa could be efficacious against organophosphate induced oxidative damage.Jun 29, 2018

Prior exposure to organophosphorus and organochlorine pesticides increases the allergic potential of environmental chemical allergens.Oct 21, 2010

The administration of vitamin B complex (in combination with a steroid) early before clinical signs of organophosphates exposure are manifest is effective in alleviating neuropathy.Aug 31, 2004

The insecticides dimethoate and deltamethrin have an adverse effect on the reproductive system of male mice.Jun 01, 2010

Vitamin C ameliorates alterations in thyroid hormones concentrations induced by subchronic coadministration of chlorpyrifos and lead in wistar rats.Jan 01, 2011

Organophosphates Related Articles

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Organophosphates

View the Evidence:
11 Abstracts with Organophosphates Research