Pancreato Protective Agents

Name	AC	CK
Anthocyanins	2	3
Chokeberry	2	3
Alpha-Lipoic Acid	1	2
Apigenin	1	2
Caffeic acid phenethyl ester	1	2
Chaga Mushroom (Inonotus obliquus)	1	2
Chrysin	1	2
Cordyceps sinensis	1	2
Curcumin	2	2
Dates	1	2
Fucoidan	1	2
Jambul	1	2
Kombucha Tea	1	2
Nettle	1	2
Parsley	1	2
Propolis: Bee	1	2
Prunella vulgaris.	1	2
Quercetin	1	2
Yarrow	1	2
Banaba	1	1
Resveratrol	1	1
Selenium	1	1
Spirulina	1	1
Thymoquinone	1	1

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Pubmed Data : Planta Med. 2014 Jun ;80(8-9):622-9. Epub 2014 May 22. PMID: 24853761

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Effects of alpha-tocopherol on acute pancreatitis.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ulus Travma Acil Cerrahi Derg. 2019 Jan ;25(1):1-6. PMID: 30742296

Article Published Date : Dec 31, 2018

Study Type : Animal Study

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Substances : Vitamin E: alpha tocopherol

Diseases : Pancreatitis

Pharmacological Actions : Pancreato Protective Agents

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Emodin may be an efficient candidate natural product for severe acute pancreatitis treatment.Nov 01, 2018

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Pubmed Data : Oncol Rep. 2018 Nov 2. Epub 2018 Nov 2. PMID: 30542707

Article Published Date : Nov 01, 2018

Study Type : Animal Study

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Substances : Emodin

Diseases : Pancreatitis

Pharmacological Actions : Anti-Inflammatory Agents, Pancreato Protective Agents

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Pubmed Data : Food Chem Toxicol. 2013 Oct ;60:328-40. Epub 2013 Jul 29. PMID: 23907022

Article Published Date : Sep 30, 2013

Study Type : Animal Study

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Substances : Kombucha Tea

Diseases : Alloxan toxicity , Diabetes Mellitus: Type 1, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Pancreato Protective Agents

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Litchi semen constituents can improve glycolipid metabolism and insulin resistance, and increase insulin sensitivity to cure T2DM.Jun 30, 2015

N. sativa and thymoquinone may prove clinically useful in the treatment of diabetics and in the protection of β-cells against oxidative stress.Nov 30, 2010

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Pubmed Data : J Diabetes. 2010 Dec ;2(4):256-66. PMID: 20923501

Article Published Date : Nov 30, 2010

Study Type : Animal Study

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Substances : Nigella sativa (aka Black Seed), Thymoquinone

Diseases : Diabetes: Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Pancreato Protective Agents, Superoxide Dismutase Up-regulation

Additional Keywords : Antioxidants, Diabetes: Oxidative Stress, Nigella sativa (aka Black Seed), Phytotherapy, Plant Extracts, thymoquinone

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Nardostachys jatamansi treatment increased the pancreatic acinar cell survival and reduced collagen deposition and pancreatic stellate cell activation.Jun 30, 2012

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Pubmed Data : BMB Rep. 2012 Jul ;45(7):402-7. PMID: 22831975

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Pubmed Data : Drug Res (Stuttg). 2018 Sep 12. Epub 2018 Sep 12. PMID: 30208495

Article Published Date : Sep 11, 2018

Study Type : Animal Study

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Substances : Rhubarb

Diseases : Diabetes: Oxidative Stress

Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Pancreato Protective Agents

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Rhubarb has protective effects in rats with acute pancreatitis.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:7321352. Epub 2018 Jul 22. PMID: 30140298

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Rhubarb

Diseases : Pancreatitis

Pharmacological Actions : Pancreato Protective Agents

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S. cumini leaf improved peripheral insulin sensitivity via stimulating/modulating β-cell insulin release.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Published Date : Feb 28, 2018

Study Type : Animal Study, In Vitro Study

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Substances : Chokeberry

Diseases : Diabetes Mellitus: Type 1

Pharmacological Actions : Hypoglycemic Agents, Pancreato Protective Agents

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This study provided new evidence supporting beneficial effects of coenzyme Q10 and L-carnitine on statin-induced pancreatic toxicity.Nov 30, 2017

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Pubmed Data : Res Pharm Sci. 2017 Dec ;12(6):434-443. PMID: 29204172

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Pubmed Data : Chin Med J (Engl). 2013 ;126(9):1647-53. PMID: 23652045

Article Published Date : Dec 31, 2012

Study Type : Animal Study

Additional Links

Substances : Prunella vulgaris

Diseases : Diabetes Mellitus: Type 2, Hyperglycemia

Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Pancreato Protective Agents, Superoxide Dismutase Up-regulation

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Virgin olive oil and Nigella sativa seeds had antihyperlipidemic and hypoglycemic effects.Feb 27, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Diabetol Metab Syndr. 2018 ;10:47. Epub 2018 Jun 14. PMID: 29942356

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Pubmed Data : J Affect Disord. 2014 Sep ;166:6-13. Epub 2014 May 4. PMID: 25012404

Article Published Date : Aug 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Folic Acid

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Pancreato Protective Agents

Additional Keywords : Increased Risk, Risk Reduction

Problem Substances : Fluoxetine (trade name Prozac)

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Ginsenoside Rg3 has the potential role in suppressing the progression of type 2 diabetes by inhibiting FFA-mediated loss of β-cells.Dec 31, 2009

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Pubmed Data : J Cell Mol Med. 2016 Oct ;20(10):1803-12. Epub 2016 Jul 22. PMID: 27444655

Article Published Date : Sep 30, 2016

Study Type : In Vitro Study

Additional Links

Substances : Shiitake Mushroom

Diseases : Diabetes: Oxidative Stress

Pharmacological Actions : Pancreato Protective Agents

Additional Keywords : Dose Response

Problem Substances : Streptozotocin

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Myricetin protects the β-cells against high glucose-induced apoptosis by inhibiting ER stress.Jan 15, 2019

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Pubmed Data : Mol Med Rep. 2018 May ;17(5):7281-7286. Epub 2018 Mar 14. PMID: 29568901

Article Published Date : Apr 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Puerarin

Diseases : Diabetes Mellitus: Type 1

Pharmacological Actions : Antioxidants, Pancreato Protective Agents

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Resveratrol inhibits ROS-promoted activation and glycolysis of pancreatic stellate cells via suppression of miR-21.Dec 31, 2017

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Pubmed Data : Biochem Biophys Res Commun. 2015 May 1 ;460(2):205-9. Epub 2015 Mar 11. PMID: 25769956

Article Published Date : Apr 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Zerumbone

Diseases : Hyperglycemia

Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents

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View the Evidence: 103 Abstracts with Pancreato Protective Agents Research

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6-shogaol can be used as a therapeutic agent for preventing complications in diabetic patients.Dec 31, 2018

A hot-water extract of rose hip exerted an anti-prediabetic effect in a rat model.Feb 08, 2017

A. vera extract exhibited pancreatic islet cell rejuvenation.Nov 30, 2017

Achillea Millefolium hydro alcoholic extract protects pancreatic cells.Dec 31, 2013

Aegle marmelos fruit extract exhibits protective effects on the pancreas.Dec 31, 2004

Alpha lipoic acid had ameliorative effects against HFCS induced pancreatic lesions.Mar 09, 2016

Amygdalin improves microcirculatory disturbance and attenuates pancreatic fibrosis.Nov 08, 2017

Anthocyanin-rich purple corn extract exerted anti-diabetic effects through protection of pancreatic β-cells and increase of insulin secretion.Jan 31, 2015

Antidiabetic activity and chemical composition of Sanbai melon seed oil.Dec 31, 2017

Aqueous extract of unfermented honeybush attenuates STZ-induced diabetes and β-cell cytotoxicity.May 31, 2014

Astaxanthin ameliorates cerulein-induced acute pancreatitis in mice.Jan 08, 2018

Baicalein protects from pancreatic injury in rats with severe acute pancreatitis.Oct 29, 2015

Balanites aegyptiaca and Petroselinum sativum aqueous extracts have antidiabetic and antioxidant effects in diabetic rats.Dec 31, 2015

Berberine chloride ameliorates oxidative stress, inflammation and apoptosis in the pancreas of Streptozotocin induced diabetic rats.Aug 22, 2017

Both resveratrol and garlic have similar property to increase insulin secretion from beta cells.Dec 31, 2015

Broccoli reduces oxidative damage to pancreatic tissue and combats hyperglycaemia in diabetic rats.Nov 30, 2017

Cabbage extracts have a pancreato-protective effect.Jan 19, 2017

Caffeic acid phenethyl ester could be used for supportive and protective therapy against pesticide intoxication.Jun 29, 2016

Chrysin treatment improves diabetes and its complications in liver, brain, and pancreasMay 12, 2015

Cordyceps sinensis could protect pancreatic beta cells from the pro-apoptotic endoplasmic reticulum stress induced by HFD-STZ.Apr 28, 2016

Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet.Jan 31, 2012

Dietary pomegranate supplement alleviates murine pancreatitis.Dec 20, 2018

Early dietary supplementation with n-6 and n-3 PUFAs can be powerfully used for protection against metabolic dysfunctions.Dec 31, 2015

Effects of alpha-tocopherol on acute pancreatitis.Dec 31, 2018

Emodin may be an efficient candidate natural product for severe acute pancreatitis treatment.Nov 01, 2018

Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes.Oct 17, 2016

Fenugreek ethanolic extract can serve as an antidote for dimethoate-induced pancreatic insult.Nov 24, 2017

Fucoidan exhibits an anti-diabetic effect mainly through attenuation of β-cell death.May 10, 2017

Fucoidan may stimulate insulin secretion and provide pancreatic protection via the cAMP signaling pathway, in vivo and in vitro.Aug 31, 2015

Ginseng extract reduces tacrolimus-induced oxidative stress by modulating autophagy in pancreatic beta cells.Jul 30, 2017

Ginsenoside Rg1 can be effective antagonistic structure and function of the pancreas injury induced by D-gal. Jun 30, 2017

Histopathologically beneficial changes in the pancreases were detected when grape seed extract was given to diabetic rats.Mar 30, 2018

Honokiol protects pancreatic β cell against high glucose and intermittent hypoxia-induced injury.Dec 31, 2017

Intermittent fasting preserves beta-cell mass in obesity-induced diabetes.Aug 29, 2017

Isolated mangiferin and naringenin exert antidiabetic effects.Jan 24, 2018

Kombucha tea attenuated oxidative stress mediated tissue damage in alloxan induced diabetic rats.Sep 30, 2013

Litchi semen constituents can improve glycolipid metabolism and insulin resistance, and increase insulin sensitivity to cure T2DM.Jun 30, 2015

Luteolin ameliorates diet-induced obesity and its comorbidities.Oct 02, 2018

Mangiferin induces islet regeneration in aged mice.Feb 28, 2018

Maternal folate supplementation counteracts bisphenol A induced Igf2 DNA hypermethylation in the offspring.Feb 05, 2017

N. sativa and thymoquinone may prove clinically useful in the treatment of diabetics and in the protection of β-cells against oxidative stress.Nov 30, 2010

Nardostachys jatamansi treatment increased the pancreatic acinar cell survival and reduced collagen deposition and pancreatic stellate cell activation.Jun 30, 2012

Naringenin could be a good anti-diabetic agent.Dec 31, 2017

Naringenin protects against acute pancreatitis in two experimental models.Dec 31, 2017

Nettle distillate regenerates pancreatic beta cells in streptozotocin-Induced diabetic rats.Feb 28, 2018

Nettle extract treatment was associated with less apoptosis in an experimental acute pancreatitis model in rats.Dec 31, 2013

Nigella sativa exerts a therapeutic protective effect in diabetes by decreasing oxidative stress and preserving pancreatic beta-cell integrity.Jun 30, 2004

Nigella sativa may be clinically useful for protecting beta-cells against oxidative stress.Sep 30, 2009

Nigerian propolis confers protection against hyperglycemia-induced oxidative stress in both liver and pancreas of adult Wistar rats.Mar 31, 2015

Oligonol protects the pancreas from Bax and PDX-1 via oxidative stress for the prevention or delaying of diabetes mellitus.Jul 12, 2016

Opuntia humifusa ameliorated cerulein-induced acute pancreatitis.Dec 31, 2013

P. alata has anti-inflammatory properties, contributing to the protection of beta cells in pancreatic islets in NOD mice.May 31, 2016

P. oleracea extract is a general tissue protective and regenerative agent and may be a novel therapeutic agent for diabetes prevention.Jan 10, 2017

Palmitoylethanolamide could be effective in type 1-diabetic patients not only as pain reliever but also in controlling the development of pathology.Dec 31, 2014

Phenylpropenoic acid glucoside from rooibos protects the beta cell mass exposed to acute diabetogenic stress.Dec 31, 2015

Polysaccharides from Inonotus obliquus may provide a valuable therapeutic option against diabetes.Dec 31, 2013

Pterostilbene can alleviate severe acute pancreatitis-induced tissue damage.Dec 31, 2015

Pterostilbene improves β-cell function and survival against cytokine stress and also prevents STZ-induced diabetes.May 31, 2017

Quercetin and quinic acid had synergistic effects in ameliorating hyperglycaemia, hyperlipidemia and insulin resistance in diabetic ratsAug 31, 2014

Rheum spiciformis showed ameliorative action on oxidative stress and hyperglycemia.Sep 11, 2018

Rhubarb has protective effects in rats with acute pancreatitis.Dec 31, 2017

S. cumini leaf improved peripheral insulin sensitivity via stimulating/modulating β-cell insulin release.Dec 31, 2015

Spikenard provided resistance to pancreatic beta-cell damage from cytokine or streptozotocin treatment.Jul 13, 2010

Spirulina fusiformis possesses significant antidiabetic and antihyperlipidemic effects.Jan 31, 2018

The significant protection effects of Panax notoginseng saponins suggested its potential in treating taurocholate induced-acute pancreatitis.Feb 04, 2018

Therapeutic potential of genistein in ovariectomy-induced pancreatic injury in diabetic rats.Aug 31, 2017

These findings suggest that berberine attenuates the severity of pancreatitis.Aug 31, 2017

These in vivo and in vitro studies provide novel insights regarding apigenin's mechanisms of action in reducing the severity of recurrent acute pancreatitis.Feb 18, 2015

These results indicate that bitter melon polysaccharide may be useful as an anti-diabetic agent.Apr 09, 2018

This study confirms the anti-diabetic activity of aronia berry.Feb 28, 2018

This study provided new evidence supporting beneficial effects of coenzyme Q10 and L-carnitine on statin-induced pancreatic toxicity.Nov 30, 2017

This study revealed that chokeberry could reduce pancreas swelling and decreased lipid peroxidation and adenosine deaminase activity.May 31, 2000

Pancreato Protective Agents

View the Evidence:
103 Abstracts with Pancreato Protective Agents Research