Pancreato Protective Agents

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24 Substances Researched for Pancreato Protective Agents
NameACCKFocus
Anthocyanins23Locked
Chokeberry23Locked
Alpha-Lipoic Acid12Locked
Apigenin12Locked
Caffeic acid phenethyl ester12Locked
Chaga Mushroom (Inonotus obliquus)12Locked
Chrysin12Locked
Cordyceps sinensis12Locked
Curcumin22Locked
Dates12Locked
Fucoidan12Locked
Jambul 12Locked
Kombucha Tea12Locked
Nettle12Locked
Parsley12Locked
Propolis: Bee12Locked
Prunella vulgaris.12Locked
Quercetin12Locked
Yarrow12Locked
Banaba11Locked
Resveratrol11Locked
Selenium11Locked
Spirulina11Locked
Thymoquinone11Locked

View the Evidence:
98 Abstracts with Pancreato Protective Agents Research

[+]

A hot-water extract of rose hip exerted an anti-prediabetic effect in a rat model.Feb 08, 2017

Pubmed Data : J Sci Food Agric. 2017 Feb 9. Epub 2017 Feb 9. PMID: 28182280
Article Published Date : Feb 08, 2017
Study Type : Animal Study
Additional Links
Substances : Rose Hips
Diseases : Advanced Glycation End products (AGE), Prediabetes
Pharmacological Actions : Anti-Glycation Agents, Pancreato Protective Agents
Additional Keywords : Risk Reduction
[+]

A. vera extract exhibited pancreatic islet cell rejuvenation.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacognosy Res. 2017 Dec ;9(Suppl 1):S99-S104. PMID: 29333050
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Aloe Vera
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Pharmacological Actions : Pancreato Protective Agents
[+]

Achillea Millefolium hydro alcoholic extract protects pancreatic cells.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Cell Med. 2014 ;3(4):255-62. PMID: 25635252
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Yarrow
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Interleukin-1 beta downregulation, Pancreato Protective Agents
Additional Keywords : Gene Expression Regulation, Plant Extracts
[+]

Alpha lipoic acid had ameliorative effects against HFCS induced pancreatic lesions.Mar 09, 2016

Pubmed Data : Pancreatology. 2016 Mar 10. Epub 2016 Mar 10. PMID: 27025195
Article Published Date : Mar 09, 2016
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
Problem Substances : High Fructose Corn Syrup
[+]

Amygdalin improves microcirculatory disturbance and attenuates pancreatic fibrosis.Nov 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Chin Med Assoc. 2017 Nov 9. Epub 2017 Nov 9. PMID: 29129515
Article Published Date : Nov 08, 2017
Study Type : Animal Study
Additional Links
Substances : Amygdalin
Diseases : Pancreatitis
Pharmacological Actions : Anti-Fibrotic, Pancreato Protective Agents
[+]

Anthocyanin-rich purple corn extract exerted anti-diabetic effects through protection of pancreatic β-cells and increase of insulin secretion.Jan 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2015 Feb ;9(1):22-9. Epub 2015 Jan 28. PMID: 25671064
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : Corn: Purple
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin-releasing, Pancreato Protective Agents
[+]

Antidiabetic activity and chemical composition of Sanbai melon seed oil.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:5434156. Epub 2018 May 2. PMID: 29853958
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Honeydew (melon)
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Antioxidants, Hepatoprotective, Hypoglycemic Agents, Hypolipidemic, Pancreato Protective Agents, Renoprotective
Additional Keywords : Antioxidants, Diabetes Mellitus: Type 1, Hepatoprotective, Honeydew (melon), Hypoglycemic Agents
[+]

Aqueous extract of unfermented honeybush attenuates STZ-induced diabetes and β-cell cytotoxicity.May 31, 2014

Pubmed Data : Planta Med. 2014 Jun ;80(8-9):622-9. Epub 2014 May 22. PMID: 24853761
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Honeybush
Diseases : Diabetes Mellitus: Type 1, Oxidative Stress
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Pancreato Protective Agents
Additional Keywords : Drug: Metformin, Plant Extracts, Xanthones
[+]

Astaxanthin ameliorates cerulein-induced acute pancreatitis in mice.Jan 08, 2018

Pubmed Data : Int Immunopharmacol. 2018 Jan 9 ;56:18-28. Epub 2018 Jan 9. PMID: 29328945
Article Published Date : Jan 08, 2018
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Pancreatitis
Pharmacological Actions : Pancreato Protective Agents
[+]

Baicalein protects from pancreatic injury in rats with severe acute pancreatitis.Oct 29, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Biophys Res Commun. 2015 Oct 30 ;466(4):664-9. Epub 2015 Sep 21. PMID: 26393905
Article Published Date : Oct 29, 2015
Study Type : Animal Study
Additional Links
Diseases : Pancreatitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Pancreato Protective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Balanites aegyptiaca and Petroselinum sativum aqueous extracts have antidiabetic and antioxidant effects in diabetic rats.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Res. 2016 ;2016:8408326. Epub 2016 Feb 25. PMID: 27019854
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Dates, Parsley
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Pancreato Protective Agents
[+]

Berberine chloride ameliorates oxidative stress, inflammation and apoptosis in the pancreas of Streptozotocin induced diabetic rats.Aug 22, 2017

Pubmed Data : Biomed Pharmacother. 2017 Aug 23 ;95:175-185. Epub 2017 Aug 23. PMID: 28843149
Article Published Date : Aug 22, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Hypoglycemic Agents, NF-kappaB Inhibitor, Pancreato Protective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Diabetes Mellitus: Type 1
[+]

Both resveratrol and garlic have similar property to increase insulin secretion from beta cells.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:360. Epub 2016 Aug 13. PMID: 27790139
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Garlic, Resveratrol
Diseases : Diabetes Mellitus: Type 1, Diabetic Complications
Pharmacological Actions : Antioxidants, Hepatoprotective, Pancreato Protective Agents
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Broccoli reduces oxidative damage to pancreatic tissue and combats hyperglycaemia in diabetic rats.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Prev Nutr Food Sci. 2017 Dec ;22(4):277-284. Epub 2017 Dec 31. PMID: 29333379
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Broccoli
Diseases : Diabetes Mellitus: Type 2, DNA damage
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
[+]

Cabbage extracts have a pancreato-protective effect.Jan 19, 2017

Pubmed Data : Nat Prod Res. 2017 Jan 20:1-4. Epub 2017 Jan 20. PMID: 28107794
Article Published Date : Jan 19, 2017
Study Type : Animal Study
Additional Links
Substances : Cabbage
Diseases : Alcohol Toxicity , Pancreatitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Pancreato Protective Agents
Additional Keywords : Alcohol Toxicity, Anti-Inflammatory Agents, Antioxidants, Cabbage, Pancreatitis, Plant Extracts
[+]

Caffeic acid phenethyl ester could be used for supportive and protective therapy against pesticide intoxication.Jun 29, 2016

Pubmed Data : Biochem Genet. 2016 Jun 30. Epub 2016 Jun 30. PMID: 27365043
Article Published Date : Jun 29, 2016
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Pesticide Toxicity
Pharmacological Actions : Cytoprotective, Pancreato Protective Agents
Problem Substances : Dichlorvos
[+]

Chrysin treatment improves diabetes and its complications in liver, brain, and pancreasMay 12, 2015

Pubmed Data : Can J Physiol Pharmacol. 2015 May 13:1-6. Epub 2015 May 13. PMID: 26863330
Article Published Date : May 12, 2015
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Diabetes Mellitus: Type 1, Diabetic Complications
Pharmacological Actions : Hepatoprotective, Neuroprotective Agents, Pancreato Protective Agents
Additional Keywords : Dose Response
[+]

Cordyceps sinensis could protect pancreatic beta cells from the pro-apoptotic endoplasmic reticulum stress induced by HFD-STZ.Apr 28, 2016

Pubmed Data : Can J Diabetes. 2016 Apr 29. Epub 2016 Apr 29. PMID: 27140306
Article Published Date : Apr 28, 2016
Study Type : Animal Study
Additional Links
Substances : Cordyceps sinensis
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Apoptotic, Hypoglycemic Agents, Pancreato Protective Agents
[+]

Dietary pomegranate supplement alleviates murine pancreatitis.Dec 20, 2018

Pubmed Data : J Nutr Biochem. 2018 Dec 21 ;66:17-28. Epub 2018 Dec 21. PMID: 30708236
Article Published Date : Dec 20, 2018
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Pancreatitis
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation, Pancreato Protective Agents
[+]

Early dietary supplementation with n-6 and n-3 PUFAs can be powerfully used for protection against metabolic dysfunctions.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Endocrinol. 2016 ;2016:9242319. Epub 2016 Dec 5. PMID: 28050167
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Essential Fatty Acids, Polyunsaturated Fatty Acids (PUFAs)
Diseases : Metabolic Diseases, Obesity
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
Problem Substances : Monosodium Glutamate (MSG)
[+]

Effects of alpha-tocopherol on acute pancreatitis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ulus Travma Acil Cerrahi Derg. 2019 Jan ;25(1):1-6. PMID: 30742296
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin E: alpha tocopherol
Diseases : Pancreatitis
Pharmacological Actions : Pancreato Protective Agents
[+]

Emodin may be an efficient candidate natural product for severe acute pancreatitis treatment.Nov 01, 2018

Pubmed Data : Oncol Rep. 2018 Nov 2. Epub 2018 Nov 2. PMID: 30542707
Article Published Date : Nov 01, 2018
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Pancreatitis
Pharmacological Actions : Anti-Inflammatory Agents, Pancreato Protective Agents
[+]

Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes.Oct 17, 2016

Pubmed Data : Clin Hemorheol Microcirc. 2016 Oct 18. Epub 2016 Aug 18. PMID: 27767974
Article Published Date : Oct 17, 2016
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Inflammatory Agents, Pancreato Protective Agents
[+]

Fenugreek ethanolic extract can serve as an antidote for dimethoate-induced pancreatic insult.Nov 24, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 Nov 25. Epub 2017 Nov 25. PMID: 29177779
Article Published Date : Nov 24, 2017
Study Type : Animal Study
Additional Links
Substances : Fenugreek
Pharmacological Actions : Pancreato Protective Agents
Additional Keywords : Plant Extracts
Problem Substances : Dimethoate
[+]

Fucoidan exhibits an anti-diabetic effect mainly through attenuation of β-cell death.May 10, 2017

Pubmed Data : Mol Nutr Food Res. 2017 May 11. Epub 2017 May 11. PMID: 28493611
Article Published Date : May 10, 2017
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Pancreato Protective Agents
Additional Keywords : Diabetes mellitus: Type 2, Fucoidan, Pancreato Protective Agents
[+]

Fucoidan may stimulate insulin secretion and provide pancreatic protection via the cAMP signaling pathway, in vivo and in vitro.Aug 31, 2015

Pubmed Data : Mol Med Rep. 2015 Sep ;12(3):4501-7. Epub 2015 Jun 23. PMID: 26130492
Article Published Date : Aug 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Pancreatic Diseases
Pharmacological Actions : Insulin-releasing, Pancreato Protective Agents
Additional Keywords : Dose Response
[+]

Ginseng extract reduces tacrolimus-induced oxidative stress by modulating autophagy in pancreatic beta cells.Jul 30, 2017

Pubmed Data : Lab Invest. 2017 Jul 31. Epub 2017 Jul 31. PMID: 28759009
Article Published Date : Jul 30, 2017
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Mitochondrial Dysfunction , Oxidative Stress
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
Problem Substances : Tacrolimus
[+]

Ginsenoside Rg1 can be effective antagonistic structure and function of the pancreas injury induced by D-gal. Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2017 Jul ;14(1):616-622. Epub 2017 May 25. PMID: 28672975
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Pancreato Protective Agents
[+]

Histopathologically beneficial changes in the pancreases were detected when grape seed extract was given to diabetic rats.Mar 30, 2018

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2018 Mar 31 ;64(4):92-97. Epub 2018 Mar 31. PMID: 29631689
Article Published Date : Mar 30, 2018
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents
[+]

Honokiol protects pancreatic β cell against high glucose and intermittent hypoxia-induced injury.Dec 31, 2017

Pubmed Data : Biomed Pharmacother. 2018 Jan ;97:1229-1237. Epub 2017 Nov 13. PMID: 29145148
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Diabetes Mellitus: Type 2, Hypoxia, Sleep Apnea: Obstructive
Pharmacological Actions : Antioxidants, Nrf2 activation, Pancreato Protective Agents
[+]

Intermittent fasting preserves beta-cell mass in obesity-induced diabetes.Aug 29, 2017

Pubmed Data : Autophagy. 2017 Aug 30:0. Epub 2017 Aug 30. PMID: 28853981
Article Published Date : Aug 29, 2017
Study Type : Animal Study
Additional Links
Diseases : Hyperglycemia, Insulin Resistance, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Pancreato Protective Agents
[+]

Isolated mangiferin and naringenin exert antidiabetic effects.Jan 24, 2018

Pubmed Data : Chem Biol Interact. 2018 Jan 25 ;280:33-44. Epub 2017 Dec 6. PMID: 29223569
Article Published Date : Jan 24, 2018
Study Type : Animal Study
Additional Links
Substances : Mangiferin, Naringenin
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Hepatoprotective, Hypoglycemic Agents, Hypolipidemic, Pancreato Protective Agents
Additional Keywords : Antioxidants, Diabetes mellitus: Type 2, Hepatoprotective, Hypoglycemic Agents, Hypolipidemic, Mangiferin, Naringenin, Pancreato Protective Agents
[+]

Kombucha tea attenuated oxidative stress mediated tissue damage in alloxan induced diabetic rats.Sep 30, 2013

Pubmed Data : Food Chem Toxicol. 2013 Oct ;60:328-40. Epub 2013 Jul 29. PMID: 23907022
Article Published Date : Sep 30, 2013
Study Type : Animal Study
Additional Links
Substances : Kombucha Tea
Diseases : Alloxan toxicity , Diabetes Mellitus: Type 1, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Pancreato Protective Agents
[+]

Litchi semen constituents can improve glycolipid metabolism and insulin resistance, and increase insulin sensitivity to cure T2DM.Jun 30, 2015

Pubmed Data : Zhong Yao Cai. 2015 Jul ;38(7):1466-71. PMID: 26946845
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Litchi
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention, Insulin Resistance
Pharmacological Actions : Insulin Sensitizers, MicroRNA modulator, Pancreato Protective Agents
Additional Keywords : Diabetes mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention, Insulin Resistance, Insulin Sensitizers, Litchi, Plant Extracts
[+]

Luteolin ameliorates diet-induced obesity and its comorbidities.Oct 02, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Oct 3 ;10(10). Epub 2018 Oct 3. PMID: 30282902
Article Published Date : Oct 02, 2018
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Fibrosis, Hepatic Steatosis, Insulin Resistance, Obesity
Pharmacological Actions : Anti-Fibrotic, Pancreato Protective Agents
Additional Keywords : Anti-Obesity Agents
[+]

Mangiferin induces islet regeneration in aged mice.Feb 28, 2018

Pubmed Data : Int J Mol Med. 2018 Mar 1. Epub 2018 Mar 1. PMID: 29512742
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents
Additional Keywords : Anti-Apoptotic, Mangiferin, Pancreato Protective Agents
[+]

Maternal folate supplementation counteracts bisphenol A induced Igf2 DNA hypermethylation in the offspring.Feb 05, 2017

Pubmed Data : J Appl Toxicol. 2017 Feb 6. Epub 2017 Feb 6. PMID: 28165156
Article Published Date : Feb 05, 2017
Study Type : Animal Study
Additional Links
Substances : Folate, Folate: Dietary
Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures
Pharmacological Actions : Pancreato Protective Agents
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Folate, Prenatal Chemical Exposures, Risk Reduction
Problem Substances : Bisphenol A
[+]

N. sativa and thymoquinone may prove clinically useful in the treatment of diabetics and in the protection of β-cells against oxidative stress.Nov 30, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes. 2010 Dec ;2(4):256-66. PMID: 20923501
Article Published Date : Nov 30, 2010
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed), Thymoquinone
Diseases : Diabetes: Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Pancreato Protective Agents, Superoxide Dismutase Up-regulation
Additional Keywords : Antioxidants, Diabetes: Oxidative Stress, Nigella sativa (aka Black Seed), Phytotherapy, Plant Extracts, thymoquinone
[+]

Nardostachys jatamansi treatment increased the pancreatic acinar cell survival and reduced collagen deposition and pancreatic stellate cell activation.Jun 30, 2012

Pubmed Data : BMB Rep. 2012 Jul ;45(7):402-7. PMID: 22831975
Article Published Date : Jun 30, 2012
Study Type : Animal Study
Additional Links
Substances : Spikenard
Diseases : Alcohol Toxicity , Pancreatitis
Pharmacological Actions : Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Naringenin protects against acute pancreatitis in two experimental models.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2018 ;2018:3232491. Epub 2018 Apr 8. PMID: 29849486
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Pancreatitis
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Malondialdehyde Down-regulation, Nrf2 activation, Pancreato Protective Agents
[+]

Nettle distillate regenerates pancreatic beta cells in streptozotocin-Induced diabetic rats.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Med Sci. 2018 Mar ;43(2):174-183. PMID: 29749986
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Nettle
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Pancreato Protective Agents, Regenerative
Additional Keywords : Plant Extracts
[+]

Nettle extract treatment was associated with less apoptosis in an experimental acute pancreatitis model in rats.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Med. 2014 ;7(5):1313-8. Epub 2014 May 15. PMID: 24995088
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Nettle
Diseases : Pancreatitis
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Nigella sativa exerts a therapeutic protective effect in diabetes by decreasing oxidative stress and preserving pancreatic beta-cell integrity.Jun 30, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Rec A Discov Mol Cell Evol Biol. 2004 Jul ;279(1):685-91. PMID: 15224410
Article Published Date : Jun 30, 2004
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Diabetes: Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Nigella sativa may be clinically useful for protecting beta-cells against oxidative stress.Sep 30, 2009

Pubmed Data : J Mol Histol. 2009 Oct ;40(5-6):379-85. Epub 2010 Jan 5. PMID: 20049514
Article Published Date : Sep 30, 2009
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Diabetes: Oxidative Stress
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
Additional Keywords : Phytotherapy
[+]

Nigerian propolis confers protection against hyperglycemia-induced oxidative stress in both liver and pancreas of adult Wistar rats.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Intercult Ethnopharmacol. 2015 Apr-Jun;4(2):102-8. Epub 2015 Feb 16. PMID: 26401394
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Propolis: Bee
Diseases : High Cholesterol, Hyperglycemia, Oxidative Stress, Triglycerides: Elevated
Pharmacological Actions : Anticholesteremic Agents, Hepatoprotective, Hypolipidemic, Malondialdehyde Down-regulation, Pancreato Protective Agents, Superoxide Dismutase Up-regulation
Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs
[+]

Oligonol protects the pancreas from Bax and PDX-1 via oxidative stress for the prevention or delaying of diabetes mellitus.Jul 12, 2016

Pubmed Data : Food Funct. 2016 Jul 13 ;7(7):3056-63. PMID: 27248500
Article Published Date : Jul 12, 2016
Study Type : Animal Study
Additional Links
Substances : Lychee
Diseases : Diabetic Complications, Oxidative Stress
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Opuntia humifusa ameliorated cerulein-induced acute pancreatitis.Dec 31, 2013

Pubmed Data : Pancreas. 2014 Jan ;43(1):118-27. PMID: 24326366
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Pancreatitis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

P. alata has anti-inflammatory properties, contributing to the protection of beta cells in pancreatic islets in NOD mice.May 31, 2016

Pubmed Data : Int Immunopharmacol. 2016 Jun ;35:127-136. Epub 2016 Apr 16. PMID: 27039211
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Diabetes Mellitus: Type 1: Prevention, Lipid Peroxidation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Pancreato Protective Agents
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

P. oleracea extract is a general tissue protective and regenerative agent and may be a novel therapeutic agent for diabetes prevention.Jan 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jan 11 ;17(1):37. Epub 2017 Jan 11. PMID: 28077129
Article Published Date : Jan 10, 2017
Study Type : Animal Study
Additional Links
Substances : Purslane
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention, Diabetic Complications
Pharmacological Actions : Hypoglycemic Agents, Interleukin-6 Downregulation, Pancreato Protective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Palmitoylethanolamide could be effective in type 1-diabetic patients not only as pain reliever but also in controlling the development of pathology.Dec 31, 2014

Pubmed Data : CNS Neurol Disord Drug Targets. 2015 ;14(4):452-62. PMID: 25921749
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Analgesics, Pancreato Protective Agents
[+]

Phenylpropenoic acid glucoside from rooibos protects the beta cell mass exposed to acute diabetogenic stress.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(6):e0157604. Epub 2016 Jun 14. PMID: 27299564
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Pancreato Protective Agents
[+]

Polysaccharides from Inonotus obliquus may provide a valuable therapeutic option against diabetes.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2014 ;2014:841496. Epub 2014 Jun 30. PMID: 25093030
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Hypolipidemic, Pancreato Protective Agents
[+]

Pterostilbene can alleviate severe acute pancreatitis-induced tissue damage.Dec 31, 2015

Pubmed Data : Genet Mol Res. 2016 ;15(3). Epub 2016 Aug 12. PMID: 27525946
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Pancreatitis: Chronic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Pancreato Protective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Pterostilbene improves β-cell function and survival against cytokine stress and also prevents STZ-induced diabetes.May 31, 2017

Pubmed Data : J Nutr Biochem. 2017 Jun ;44:11-21. Epub 2017 Mar 6. PMID: 28343084
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Nrf2 activation, Pancreato Protective Agents
[+]

Quercetin and quinic acid had synergistic effects in ameliorating hyperglycaemia, hyperlipidemia and insulin resistance in diabetic ratsAug 31, 2014

Pubmed Data : Food Chem Toxicol. 2014 Sep ;71:183-96. Epub 2014 Jun 19. PMID: 24953551
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Diabetes Mellitus: Type 2, Diabetic Complications, Hyperglycemia, Hyperlipidemia, Insulin Resistance, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective, Pancreato Protective Agents, Renoprotective
Additional Keywords : Natural Substance Synergy, Significant Treatment Outcome
[+]

Rheum spiciformis showed ameliorative action on oxidative stress and hyperglycemia.Sep 11, 2018

Pubmed Data : Drug Res (Stuttg). 2018 Sep 12. Epub 2018 Sep 12. PMID: 30208495
Article Published Date : Sep 11, 2018
Study Type : Animal Study
Additional Links
Substances : Rhubarb
Diseases : Diabetes: Oxidative Stress
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Pancreato Protective Agents
[+]

Rhubarb has protective effects in rats with acute pancreatitis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:7321352. Epub 2018 Jul 22. PMID: 30140298
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Rhubarb
Diseases : Pancreatitis
Pharmacological Actions : Pancreato Protective Agents
[+]

S. cumini leaf improved peripheral insulin sensitivity via stimulating/modulating β-cell insulin release.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:48. Epub 2016 Mar 10. PMID: 27014062
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Jambul
Diseases : Insulin Resistance, MSG Toxicity, Obesity
Pharmacological Actions : Insulin Sensitizers, Pancreato Protective Agents
Problem Substances : Monosodium Glutamate (MSG)
[+]

Spikenard provided resistance to pancreatic beta-cell damage from cytokine or streptozotocin treatment.Jul 13, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2010 Jul 14 ;16(26):3249-57. PMID: 20614480
Article Published Date : Jul 13, 2010
Study Type : Animal Study
Additional Links
Substances : Spikenard
Diseases : Diabetic Complications
Pharmacological Actions : Hypoglycemic Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Spirulina fusiformis possesses significant antidiabetic and antihyperlipidemic effects.Jan 31, 2018

Pubmed Data : 3 Biotech. 2018 Feb ;8(2):129. Epub 2018 Feb 13. PMID: 29450119
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Diabetic Complications
Pharmacological Actions : Hepatoprotective, Hypoglycemic Agents, Hypolipidemic, Pancreato Protective Agents, Renoprotective
[+]

The significant protection effects of Panax notoginseng saponins suggested its potential in treating taurocholate induced-acute pancreatitis.Feb 04, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Feb 5 ;18(1):51. Epub 2018 Feb 5. PMID: 29402262
Article Published Date : Feb 04, 2018
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng
Diseases : Pancreatitis
Pharmacological Actions : Enzyme Inhibitors: Pancreatic Amylase, Enzyme Inhibitors: Pancreatic Lipase, Pancreato Protective Agents
[+]

Therapeutic potential of genistein in ovariectomy-induced pancreatic injury in diabetic rats.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2017 Sep ;20(9):1009-1015. PMID: 29085595
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Hyperglycemia, Postmenopausal Disorders
Pharmacological Actions : Hypoglycemic Agents, Pancreato Protective Agents
[+]

These findings suggest that berberine attenuates the severity of pancreatitis.Aug 31, 2017

Pubmed Data : Pancreas. 2017 Sep ;46(8):1046-1055. PMID: 28797013
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Pancreatitis
Pharmacological Actions : Enzyme Inhibitors: Pancreatic Amylase, Enzyme Inhibitors: Pancreatic Lipase, Pancreato Protective Agents
[+]

These in vivo and in vitro studies provide novel insights regarding apigenin's mechanisms of action in reducing the severity of recurrent acute pancreatitis.Feb 18, 2015

Pubmed Data : J Surg Res. 2015 Feb 19. Epub 2015 Feb 19. PMID: 25799526
Article Published Date : Feb 18, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Pancreatitis, Pancreatitis: Chronic
Pharmacological Actions : Pancreato Protective Agents
Additional Keywords : Dose Response, Parathyroid-hormone-related Protein, Recurrence Risk
[+]

These results indicate that bitter melon polysaccharide may be useful as an anti-diabetic agent.Apr 09, 2018

Pubmed Data : Int J Biol Macromol. 2018 Apr 10 ;115:45-52. Epub 2018 Apr 10. PMID: 29649536
Article Published Date : Apr 09, 2018
Study Type : Animal Study
Additional Links
Substances : Bitter Melon
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Pancreato Protective Agents
Additional Keywords : Polysaccharides
[+]

This study confirms the anti-diabetic activity of aronia berry.Feb 28, 2018

Pubmed Data : J Med Food. 2018 Mar ;21(3):244-253. Epub 2018 Feb 22. PMID: 29470134
Article Published Date : Feb 28, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chokeberry
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents, Pancreato Protective Agents
[+]

This study provided new evidence supporting beneficial effects of coenzyme Q10 and L-carnitine on statin-induced pancreatic toxicity.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Res Pharm Sci. 2017 Dec ;12(6):434-443. PMID: 29204172
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10, L-Carnitine
Diseases : Statin-Induced Pathologies
Pharmacological Actions : Pancreato Protective Agents
Problem Substances : Statin Drugs
[+]

This study revealed that chokeberry could reduce pancreas swelling and decreased lipid peroxidation and adenosine deaminase activity.May 31, 2000

Pubmed Data : Pol Merkur Lekarski. 2000 Jun ;8(48):395-8. PMID: 10967916
Article Published Date : May 31, 2000
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Chokeberry
Diseases : Lipid Peroxidation, Pancreatitis
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
[+]

Tinospora cordifolia polysaccharide possesses hypoglycemic, glucose oxidizing, hypolipidemic and β-cell regenerative properties.Jan 04, 2016

Pubmed Data : Chem Biol Interact. 2016 Jan 5 ;243:45-53. Epub 2015 Aug 23. PMID: 26616445
Article Published Date : Jan 04, 2016
Study Type : Animal Study
Additional Links
Substances : Guduchi
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Pancreato Protective Agents, Regenerative
Additional Keywords : Plant Extracts, Polysaccharides
[+]

Triterpenic acid from Prunella vulgaris L. has an anti-diabetic effect, by controlling blood glucose and antioxidants.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med J (Engl). 2013 ;126(9):1647-53. PMID: 23652045
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Diabetes Mellitus: Type 2, Hyperglycemia
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Pancreato Protective Agents, Superoxide Dismutase Up-regulation
[+]

Walnut leaf powder anti-hyperglycaemic, anti-hyperlipidaemic, and organ-protective effects.Mar 29, 2017

Pubmed Data : Food Chem Toxicol. 2017 Mar 30. Epub 2017 Mar 30. PMID: 28366844
Article Published Date : Mar 29, 2017
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Diabetes Mellitus: Type 2, Diabetic Complications
Pharmacological Actions : Hepatoprotective, Hypoglycemic Agents, Hypolipidemic, Pancreato Protective Agents, Renoprotective
[+]

A review of the phytochemical, anti-diabetic and cardiovascular properties of nettle.Sep 23, 2018

Pubmed Data : Mini Rev Med Chem. 2018 Sep 24. Epub 2018 Sep 24. PMID: 30246639
Article Published Date : Sep 23, 2018
Study Type : Review
Additional Links
Substances : Nettle
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2, Diabetic Complications
Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Cardioprotective, Nitric Oxide Enhancer, Pancreato Protective Agents
[+]

Apigenin could attenuate the STZ-induced oxidative damages in pancreatic beta cells.Feb 07, 2017

Pubmed Data : In Vitro Cell Dev Biol Anim. 2017 Feb 8. Epub 2017 Feb 8. PMID: 28181104
Article Published Date : Feb 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
[+]

Black adzuki bean extract protects pancreatic beta cells and improves glucose tolerance.Apr 30, 2016

Pubmed Data : J Med Food. 2016 May ;19(5):442-9. Epub 2016 Apr 12. PMID: 27070495
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Black Bean
Diseases : Diabetes Mellitus: Type 2, Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents, Pancreato Protective Agents
[+]

Chokeberry anthocyanin extract proved to have a role in protecting pancreatic β-cells increasing the SOD, CAT, GPx, and GSH levelsDec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2015 ;2015:429075. Epub 2015 May 31. PMID: 26113953
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins, Chokeberry
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Pancreato Protective Agents, Superoxide Dismutase Up-regulation
[+]

Coenzyme Q10 suppresses apoptosis of mouse pancreatic β-cell line MIN6.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetol Metab Syndr. 2018 ;10:47. Epub 2018 Jun 14. PMID: 29942356
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Coenzyme Q10
Diseases : Diabetic Complications
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents
[+]

Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells.Sep 01, 2015

Pubmed Data : Apoptosis. 2015 Sep 2. Epub 2015 Sep 2. PMID: 26330141
Article Published Date : Sep 01, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents
[+]

Epigallocatechin-3-gallate has antioxidant effects on the aTC1-6 pancreatic alpha cell line.Nov 04, 2017

Pubmed Data : Biochem Biophys Res Commun. 2017 Nov 5. Epub 2017 Nov 5. PMID: 29117537
Article Published Date : Nov 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Hypoglycemia
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
[+]

Folic acid supplementation in patients taking SSRIs may reduce the risk of new onset diabetes via protection of normal beta cell function.Aug 31, 2014

Pubmed Data : J Affect Disord. 2014 Sep ;166:6-13. Epub 2014 May 4. PMID: 25012404
Article Published Date : Aug 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Pancreato Protective Agents
Additional Keywords : Increased Risk, Risk Reduction
Problem Substances : Fluoxetine (trade name Prozac)
[+]

Ginsenoside Rg3 has the potential role in suppressing the progression of type 2 diabetes by inhibiting FFA-mediated loss of β-cells.Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2010 Jan ;46(1):30-5. Epub 2009 Dec 29. PMID: 20104262
Article Published Date : Dec 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Pancreato Protective Agents
[+]

Hibiscus petals as a natural source and functional food of potential therapeutics to protect pancreatic β-cells in experimental diabetes mellitus.Aug 15, 2018

Pubmed Data : J Ethnopharmacol. 2018 Aug 16 ;227:8-17. Epub 2018 Aug 16. PMID: 30120944
Article Published Date : Aug 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hibiscus rosa-sinensis
Diseases : Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Pancreato Protective Agents
[+]

Lagerstroemia speciosa leaves were effective in the treatment of diabetes.Apr 30, 2013

Pubmed Data : Mol Med Rep. 2013 May ;7(5):1607-12. Epub 2013 Mar 26. PMID: 23545843
Article Published Date : Apr 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Banaba
Diseases : Diabetes Mellitus: Type 1, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Cytoprotective, Insulin-releasing, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Lentinan may be a potential pharmacological agent for preventing pancreatic β‐cell damage caused by oxidative stress.Sep 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2016 Oct ;20(10):1803-12. Epub 2016 Jul 22. PMID: 27444655
Article Published Date : Sep 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Shiitake Mushroom
Diseases : Diabetes: Oxidative Stress
Pharmacological Actions : Pancreato Protective Agents
Additional Keywords : Dose Response
Problem Substances : Streptozotocin
[+]

Myricetin protects the β-cells against high glucose-induced apoptosis by inhibiting ER stress.Jan 15, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetes Metab J. 2019 Jan 16. Epub 2019 Jan 16. PMID: 30688049
Article Published Date : Jan 15, 2019
Study Type : In Vitro Study
Additional Links
Substances : Myricetin
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Pancreato Protective Agents
[+]

Naringin protects against HIV-1 protease inhibitors-induced pancreatic β-cell dysfunction and apoptosis.Jan 04, 2016

Pubmed Data : Mol Cell Endocrinol. 2016 12 5 ;437:1-10. Epub 2016 Aug 2. PMID: 27496642
Article Published Date : Jan 04, 2016
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : HIV Drug-Induced Toxicity , Lipid Peroxidation
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Pancreato Protective Agents
[+]

Naringin protects pancreatic β-cells against oxidative stress-induced apoptosis. Feb 28, 2018

Pubmed Data : Mol Nutr Food Res. 2018 Mar ;62(5). Epub 2018 Feb 5. PMID: 29314619
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Diabetes: Oxidative Stress, Diabetic Complications
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Pancreato Protective Agents
[+]

Phytonutrient genistein is a survival factor for pancreatic β-cells via GPR30-mediated mechanism.Jul 31, 2018

Pubmed Data : J Nutr Biochem. 2018 Aug ;58:59-70. Epub 2018 May 12. PMID: 29885598
Article Published Date : Jul 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Genistein
Diseases : Diabetic Complications
Pharmacological Actions : Pancreato Protective Agents
[+]

Polysaccharides from chaga mushroom may have potential merit as a medicinal food for the prevention of diabetes.Sep 21, 2016

Pubmed Data : Mol Med Rep. 2016 Sep 22. Epub 2016 Sep 22. PMID: 27667194
Article Published Date : Sep 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus)
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
[+]

Puerarin may be effective in preventing islet cells from the toxic action of reactive oxygen species in diabetes.Jan 03, 2006

Pubmed Data : Eur J Pharmacol. 2006 Jan 4 ;529(1-3):1-7. PMID: 16321378
Article Published Date : Jan 03, 2006
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents, Superoxide Dismutase Up-regulation
Problem Substances : Insulin
[+]

Puerarin promotes MIN6 cell survival by reducing cellular reactive oxygen species.Apr 30, 2018

Pubmed Data : Mol Med Rep. 2018 May ;17(5):7281-7286. Epub 2018 Mar 14. PMID: 29568901
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
[+]

Resveratrol inhibits ROS-promoted activation and glycolysis of pancreatic stellate cells via suppression of miR-21.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:1346958. Epub 2018 Apr 26. PMID: 29854071
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Fibrosis, Pancreatitis
Pharmacological Actions : MicroRNA modulator, Pancreato Protective Agents
[+]

Selenium enriched spirulina protects INS-1E cells from hIAPP-induced cell death through preventing ROS overproduction, mitochondrial dysfunction.May 31, 2015

Pubmed Data : Eur J Nutr. 2015 Jun ;54(4):509-22. Epub 2014 Aug 12. PMID: 25112514
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Selenium, Spirulina
Diseases : Diabetes Mellitus: Type 2: Prevention, Mitochondrial Dysfunction , Oxidative Stress
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

St. John's wort and its component hyperforin have promising therapeutic potential for limitation of immune-mediated β-cell dysfunction.Oct 21, 2016

Pubmed Data : Int J Biochem Cell Biol. 2016 Oct 22. Epub 2016 Oct 22. PMID: 27989965
Article Published Date : Oct 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Hyperforin, St. Johns Wort
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions : Anti-Inflammatory Agents, Pancreato Protective Agents
Additional Keywords : Gene Expression Regulation
[+]

This study demonstrates a novel role for natural occurring polyphenols as PDE inhibitors that enhance pancreatic β-cell function.Oct 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Endocrinol. 2014 Nov ;223(2):107-17. PMID: 25297556
Article Published Date : Oct 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Pancreato Protective Agents, Phosphodiesterase Inhibitors
Additional Keywords : Dose Response, Gene Expression Regulation
[+]

This study demonstrates the therapeutic potential and action mechanism of cirsimaritin for the prevention and treatment of type 1 diabetes mellitus.Jun 30, 2017

Pubmed Data : J Pharm Pharmacol. 2017 Jul ;69(7):875-883. Epub 2017 Apr 11. PMID: 28397263
Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thistle
Diseases : Diabetes Mellitus: Type 1: Prevention, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Bcl-2 protein down-regulation, Pancreato Protective Agents
[+]

This study that examines the impact of ginsenosides on human pancreatic islets in vitro.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Pharm Med Res. 2016 Jan ;3(1):110-119. PMID: 27547829
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Ginseng, Ginsenosides
Diseases : Hyperglycemia
Pharmacological Actions : Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Thymoquinone normalizes insulin secretion from pancreatic β-cells under glucose overload.Jan 18, 2016

Pubmed Data : Am J Physiol Endocrinol Metab. 2016 Jan 19:ajpendo.00250.2015. Epub 2016 Jan 19. PMID: 26786775
Article Published Date : Jan 18, 2016
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Pancreato Protective Agents
[+]

Zerumbone may have potential therapeutic effects against hyperglycemia-induced β cell damage in diabetes.Apr 30, 2015

Pubmed Data : Biochem Biophys Res Commun. 2015 May 1 ;460(2):205-9. Epub 2015 Mar 11. PMID: 25769956
Article Published Date : Apr 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Zerumbone
Diseases : Hyperglycemia
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents

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