Gastrointestinal Diseases

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19 Substances Researched for Gastrointestinal Diseases
NameACCKFocus
Bifidobacterium Bifidum220Locked
Milk: Fermented220Locked
Black Pepper24Locked
Resveratrol24Locked
Bacillus Clausii22Locked
Patchouli12Locked
Cannabidiol 11Locked
Cannabinoids 11Locked
EGCG (Epigallocatechin gallate)11Locked
Folate11Locked
Probiotics11Locked
Salvia divinorum11Locked
Sulforaphane11Locked
Vitamin B-1211Locked
Vitamin B-611Locked
Vitamin C11Locked
Vitamin D11Locked
Vitamin E11Locked
Yarrow10Locked
5 Problem Substances Researched for Gastrointestinal Diseases
NameACCKFocus
Sorbitol 110Locked
Wheat Germ Agglutinin (WGA)23Locked
Atorvastatin12Locked
Statin Drugs12Locked
Bisphosphonates11Locked
2 Therapeutic Actions Researched for Gastrointestinal Diseases
NameACCKFocus
Acupuncture12Locked
Electroacupuncture12Locked
2 Problematic Actions Researched for Gastrointestinal Diseases
NameACCKFocus
Vaccination: All110Locked
Vaccination: Hepatitis B110Locked

View the Evidence:
29 Abstracts with Gastrointestinal Diseases Research

[+]

Fermented milk containing B. bifidum has the potential to provide health benefits by alleviating gastric symptoms in subjects taking no medication.Mar 31, 2015

Pubmed Data : J Dairy Sci. 2015 Apr ;98(4):2277-83. Epub 2015 Jan 31. PMID: 25648808
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Substances : Bifidobacterium Bifidum, Milk: Fermented
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Microbiota, Significant Treatment Outcome
[+]

Fermented milk containing Bifidobacterium bifidum improves gastrointestinal symptoms and reduces psychological stress in FGID patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Microbiota Food Health. 2015 ;34(2):37-44. Epub 2015 Jan 21. PMID: 25918671
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Bifidobacterium Bifidum, Milk: Fermented
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Significant Treatment Outcome
[+]

Hepatitis B vaccination was statistically associated with gastrointestinal reactions including: hepatitis, gastrointestinal disease and liver function test abnormalities.Nov 01, 2002

Pubmed Data : Hepatogastroenterology. 2002 Nov-Dec;49(48):1571-5. PMID: 12397738
Article Published Date : Nov 01, 2002
Study Type : Human Study
Additional Links
Diseases : Gastrointestinal Diseases, Hepatitis, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

Individuals with autism who are stratified by presence of gastrointestinal dysfunction had elevated plasma F2t-isoprostane levels.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(7):e68444. Epub 2013 Jul 3. PMID: 23844202
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Gastrointestinal Diseases, Triglycerides: Elevated
[+]

Sorbitol intolerance associated wtih abdominal pain, bloating and diarrhea may be an under reported phenomenon. Sep 01, 1985

Pubmed Data : Am J Gastroenterol. 1985 Sep;80(9):678-81. PMID: 4036946
Article Published Date : Sep 01, 1985
Study Type : Human Study
Additional Links
Diseases : Diarrhea, Gastrointestinal Diseases, Irritable Bowel Syndrome
Problem Substances : Sorbitol
[+]

Alcohol and atorvastatin interact to adversely affect intestinal villi structure.Jan 01, 2004

Pubmed Data : Ann Univ Mariae Curie Sklodowska Med. 2004 ;59(2):38-43. PMID: 16146046
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Diseases : Alcohol Toxicity , Gastrointestinal Diseases, Statin-Induced Pathologies
Additional Keywords : Toxic Substance Synergy
Problem Substances : Atorvastatin, Statin Drugs
[+]

Black pepper has antispasmodic properties.Jun 01, 2008

Pubmed Data : Pak J Biol Sci. 2008 Jun 1;11(11):1492-6. PMID: 18817253
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Antispasmodic
Additional Keywords : Plant Extracts
[+]

Black pepper may have a therapeutic role in the treatment of gastrointestinal disorders.Dec 01, 2009

Pubmed Data : Anticancer Res. 2009 Dec;29(12):4981-8. PMID: 20828313
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Antispasmodic
[+]

Electroacupuncture was found to have regulation on immunity in rats. Dec 31, 2015

Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:1935372. Epub 2016 Aug 3. PMID: 27594888
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Gastrointestinal Diseases
Therapeutic Actions : Acupuncture, Electroacupuncture
Pharmacological Actions : Immunomodulatory
[+]

Genipin has significant gastroprotective effects and might be useful for treating and preventing gastric lesions.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2017 ;40(2):151-154. PMID: 28154253
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Gastric Ulcer, Gastrointestinal Diseases
Pharmacological Actions : Gastroprotective
[+]

Intravenous resveratrol protects against severe intestinal ischemia/reperfusion injury in rats.Jun 29, 2010

Pubmed Data : J Surg Res. 2010 Jun 29. Epub 2010 Jun 29. PMID: 20850780
Article Published Date : Jun 29, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Gastrointestinal Diseases, Intestinal Injury
[+]

Patchouli may provide gastrointestinal protection against trauma or surgical operation. Jul 01, 2009

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Jul;29(7):639-41. PMID: 19852300
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Patchouli
Diseases : Bowel Surgery, Colon Surgery, Gastrointestinal Diseases, Short Bowel Syndrome
Pharmacological Actions : Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Resveratrol attenuates intestinal injury after trauma hemmorhage. Dec 09, 2010

Pubmed Data : Shock. 2010 Dec 9. Epub 2010 Dec 9. PMID: 21192278
Article Published Date : Dec 09, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Gastrointestinal Diseases, Gastrointestinal Hemorrhage
[+]

The antispasmodic effect of Ometa cultivar shows that common gastrointestinal disorders could be treated by the functional food.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Princ Pract. 2018 ;27(2):179-185. Epub 2018 Jan 28. PMID: 29402838
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Black Currant
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Antispasmodic, Gastrointestinal Agents
[+]

Wheat lectin may be responsible for contributing to intestinal disease.May 01, 1982

Pubmed Data : Gastroenterology. 1982 May;82(5 Pt 1):838-48. PMID: 6895878
Article Published Date : May 01, 1982
Study Type : Animal Study
Additional Links
Diseases : Gastrointestinal Diseases
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

A remarkable preventive role of many vitamins like B6, B9, B12 and D on the risk of developing CRC was suggested by a large number of observational studies.May 06, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2015 May 7 ;21(17):5191-5209. PMID: 25954093
Article Published Date : May 06, 2015
Study Type : Review
Additional Links
Substances : Folate, Vitamin B-12, Vitamin B-6, Vitamin C, Vitamin D, Vitamin E
Diseases : Celiac Disease, Colorectal Cancer, Colorectal Cancer: Prevention , Gastrointestinal Diseases
Pharmacological Actions : Gastrointestinal Agents
[+]

B. clausii affects the expression of genes involved in immune response and inflammation, apoptosis and cell growth, cell differentiation.Aug 31, 2005

Pubmed Data : Eur J Gastroenterol Hepatol. 2005 Sep ;17(9):951-60. PMID: 16093873
Article Published Date : Aug 31, 2005
Study Type : In Vitro Study
Additional Links
Substances : Bacillus Clausii
Diseases : Gastrointestinal Diseases, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
Additional Keywords : Gene Expression Regulation
[+]

Bisphosphonates may induce gastrointestinal damage through the inhibition of the mevalonate pathway.Oct 01, 2001

Pubmed Data : Bone. 2001 Oct;29(4):336-43. PMID: 11595616
Article Published Date : Oct 01, 2001
Study Type : In Vitro Study
Additional Links
Diseases : Drug-Induced Toxicity: Gastrointestinal, Gastrointestinal Diseases
Additional Keywords : Mevalonate Pathway Inhibition
Problem Substances : Bisphosphonates
Adverse Pharmacological Actions : Apoptotic
[+]

Cannabinoids are promising candidates for gastrointestinal and urinary diseases.Dec 31, 2014

Pubmed Data : Handb Exp Pharmacol. 2015 ;231:423-47. PMID: 26408170
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabinoids
Diseases : Gastrointestinal Diseases, Urinary Bladder Diseases
Additional Keywords : Cannabinoid Receptors
[+]

EGCG may be useful for prevention of intestinal disorders or bacterial infection in animals/humans.Apr 30, 2016

Pubmed Data : Mol Nutr Food Res. 2016 May ;60(5):1048-58. Epub 2016 Apr 4. PMID: 26991948
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Escherichia coli Infections, Gastrointestinal Diseases
Pharmacological Actions : Antimicrobial
[+]

In this study, the therapeutic effects of chamomile were reviewed in detail.Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Electron Physician. 2016 Sep ;8(9):3024-3031. Epub 2016 Sep 20. PMID: 27790360
Article Published Date : Aug 31, 2016
Study Type : Review
Additional Links
Substances : Chamomile
Diseases : Cancers: All, Diarrhea, Gastrointestinal Diseases, Inflammation, Osteoarthritis, Premenstrual syndrome, Ulcerative Colitis
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anticarcinogenic Agents, Antidepressive Agents, Antidiarrheals, Antimicrobial, Antioxidants
Additional Keywords : Plant Extracts
[+]

Increasing dietary oat fibre decreases the permeability of intestinal mucus.Sep 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Funct Foods. 2016 Oct ;26:418-427. PMID: 27790292
Article Published Date : Sep 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fiber, Oats
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Gastroprotective
[+]

Onopordum species may exert beneficial effects against gastric inflammatory diseases.Jan 09, 2018

Pubmed Data : J Ethnopharmacol. 2018 Jan 10 ;210:469-476. Epub 2017 Sep 13. PMID: 28916191
Article Published Date : Jan 09, 2018
Study Type : In Vitro Study
Additional Links
Substances : Thistle
Diseases : Gastrointestinal Diseases, Gastrointestinal Inflammation, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Salvia divinorum has potential value for gastrointestinal disorders, including diarrhea. Sep 01, 2009

Pubmed Data : Drug News Perspect. 2009 Sep;22(7):383-92. PMID: 19890495
Article Published Date : Sep 01, 2009
Study Type : Commentary
Additional Links
Substances : Salvia divinorum
Diseases : Diarrhea, Gastrointestinal Diseases
[+]

Sulforaphane can increase the antimicrobial peptide secretion of beta-defensin 2 in intestinal cells.Oct 01, 2008

Pubmed Data : Immunology. 2008 Oct;125(2):241-51. Epub 2008 Mar 27. PMID: 18373608
Article Published Date : Oct 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Gastrointestinal Diseases, Immune Disorders: Low Immune Function, Intestinal Diseases, Low Disorders: Low TH1
Pharmacological Actions : Beta-Defensin-2 Up-Regulation, Enzyme Inhibitors, Histone deacetylase inhibitor, NF-kappaB Inhibitor
[+]

This review focuses on B. clausii clinical applications and speculates on the possible interactions among the gut barrier and immune system.Jul 31, 2016

Pubmed Data : Expert Rev Gastroenterol Hepatol. 2016 Aug ;10(8):943-8. Epub 2016 Jun 22. PMID: 27291780
Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Bacillus Clausii
Diseases : Dysbiosis, Gastrointestinal Diseases
Pharmacological Actions : Antimicrobial, Immunomodulatory
Additional Keywords : Microbiota
[+]

This review has focused on several beneficial properties of probiotics.Jul 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Trop Life Sci Res. 2016 Aug ;27(2):73-90. PMID: 27688852
Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Anxiety, Dental Caries, Depression, Gastrointestinal Diseases, Periodontal Diseases
Pharmacological Actions : Anticholesteremic Agents, Immunomodulatory, Nitric Oxide Inhibitor
[+]

Wheat lectin exhibits inflammatory and permeability-inducing effects on the human gastrointestinal lining at nanomolar concentrations via the stimulation of immune cells.Jun 01, 2009

Pubmed Data : Toxicol Appl Pharmacol. 2009 Jun 1;237(2):146-53. Epub 2009 Mar 28. PMID: 19332085
Article Published Date : Jun 01, 2009
Study Type : In Vitro Study
Additional Links
Diseases : Gastrointestinal Diseases
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

Yarrow's traditional use for gastrointestinal disorders are confirmed by recent findings.Jan 01, 2007

Pubmed Data : Wien Med Wochenschr. 2007;157(13-14):312-4. PMID: 17704978
Article Published Date : Jan 01, 2007
Additional Links
Substances : Yarrow
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Antispasmodic

Copyright: eraxion / 123RF Stock Photo

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