Depression

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116 Substances Researched for Depression
NameACCKFocus
Vitamin D890Locked
Curcumin1484Locked
St. John's Wort560Locked
Saffron653Locked
Omega-3 Fatty Acids652Locked
Homeopathic Medicine: All550Locked
DHA (Docosahexaenoic Acid)340Locked
EPA (Eicosapentaenoic Acid)340Locked
Lavender440Locked
Ayahuasca734Locked
Psilocybin532Locked
Rhodiola (Tibetan Ginseng)432Locked
Polyunsaturated Fatty Acids (PUFAs)331Locked
Kava Kava230Locked
Magnesium330Locked
SAMe (S-adenosylmethionine)230Locked
Tryptophan330Locked
Probiotics524Locked
Ginkgo biloba221Locked
Acetyl-l-carnitine220Locked
Bergamot220Locked
Chlorella (Algae)220Locked
Coffee220Locked
Docosahexaenoic acid (DHA)120Locked
Eicosapentaenoic acid (EPA) 120Locked
Fruit: All120Locked
Lavender: Essential Oil120Locked
Soy220Locked
Vegetables: All 120Locked
Rosemary416Locked
Cocoa211Locked
Lion's Mane (Hericium Erinaceus)211Locked
5-HTP (5-Hydroxytryptophan)110Locked
Blue-Green Algae110Locked
Chamomile110Locked
Coenzyme Q10110Locked
DHEA (Dehydroepiandrosterone)110Locked
Essential Fatty Acids110Locked
Eucalyptus110Locked
Fish110Locked
Frankincense110Locked
Goji110Locked
Marjoram110Locked
Motherwort110Locked
Niacin110Locked
Piperidines110Locked
Selenium110Locked
Vitamin E110Locked
Zinc110Locked
Cannabidiol 58Locked
Piperine48Locked
Melatonin46Locked
Bacopa35Locked
Polyphenols45Locked
Resveratrol35Locked
Gardenia24Locked
Fiber13Locked
Flavonoids23Locked
Green Tea23Locked
Lysergic Acid Diethylamide (LSD)33Locked
Salvia divinorum23Locked
Apigenin12Locked
Ashwagandha12Locked
Asparagus12Locked
Astaxanthin12Locked
Bamboo12Locked
Berberine12Locked
Bifidobacterium Infantis12Locked
Bifidobacterium Longum 12Locked
Bitter Orange12Locked
Black Pepper12Locked
Cannabinoids 12Locked
Cannabis12Locked
Catuaba12Locked
Chokeberry12Locked
Dandelion 12Locked
Delta-tetrahydrocannabinol (THC)12Locked
Dill12Locked
Feijoa12Locked
Fenugreek12Locked
Fisetin12Locked
Flaxseed12Locked
Geraniol 12Locked
Kratom22Locked
Krill12Locked
Lactobacillus rhamnosus 12Locked
Lettuce12Locked
Lobelia12Locked
Luteolin12Locked
Magnolia12Locked
Mango 12Locked
Moringa oleifera12Locked
Mucuna pruriens (aka Velvet Beans)12Locked
Musk (Animal)12Locked
Myricetin12Locked
Nutmeg12Locked
Onion12Locked
Panax Ginseng12Locked
Perilla 12Locked
Pycnogenol (Pine Bark)12Locked
Sesamol12Locked
Silibinin12Locked
Sulforaphane12Locked
Thistle12Locked
Tualang Honey12Locked
Valerian12Locked
ALA (Alpha-Linolenic Acid)11Locked
Anthocyanins11Locked
Catechin 11Locked
Chrysin11Locked
Curcumin: Degradiation byproducts11Locked
Folic Acid 11Locked
Graviola 11Locked
Oak11Locked
Prebiotics11Locked
St. Johns Wort21Locked
24 Problem Substances Researched for Depression
39 Therapeutic Actions Researched for Depression
8 Problematic Actions Researched for Depression
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View the Evidence:
682 Abstracts with Depression Research

[+]
Pubmed Data : J Psychopharmacol. 2014 Apr 30 ;28(6):545-552. Epub 2014 Apr 30. PMID: 24785760
Study Type : Review
Additional Links
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]
Pubmed Data : Brain Res Bull. 2016 Mar 25. Epub 2016 Mar 25. PMID: 27018165
Study Type : Review
[+]
Pubmed Data : Mod Trends Pharmacopsychiatry. 2017 ;31:56-66. Epub 2017 Jul 24. PMID: 28738351
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
[+]
Pubmed Data : Brain Res Bull. 2015 Aug 27. Epub 2015 Aug 27. PMID: 26321393
Study Type : Review
Additional Links
Substances : Melatonin
Additional Keywords : Significant Treatment Outcome
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Chem Neuroanat. 2016 Sep ;75(Pt B):43-51. Epub 2015 Aug 21. PMID: 26300312
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
[+]
Pubmed Data : Am J Geriatr Psychiatry. 2018 Nov 3. Epub 2018 Nov 3. PMID: 30527963
Study Type : Review
Additional Links
Diseases : Anxiety, Depression
Therapeutic Actions : Meditation , Tai Chi
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]
Pubmed Data : J Psychiatr Res. 2017 Dec ;95:156-178. Epub 2017 Aug 23. PMID: 28863392
Study Type : Review
Additional Links
Diseases : Anxiety, Depression
Therapeutic Actions : Meditation , Mindfullness Training
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]
Pubmed Data : Neurosci Lett. 2017 Nov 1 ;660:79-85. Epub 2017 Sep 8. PMID: 28893593
Study Type : In Vitro Study
Additional Links
Substances : Passion Flower
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]
Pubmed Data : J Holist Nurs. 2016 May 11. Epub 2016 May 11. PMID: 27170647
Study Type : Review
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Children (Basel). 2017 Feb 10 ;4(2). Epub 2017 Feb 10. PMID: 28208599
Study Type : Review
Additional Links
Therapeutic Actions : Meditation , Yoga
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Pubmed Data : CNS Neurol Disord Drug Targets. 2018 07 1. Epub 2018 Jul 1. PMID: 29962349
Study Type : Review
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Pubmed Data : Adv Mind Body Med. 2017 Summer;31(3):8-16. PMID: 28987035
Study Type : Review
Additional Links
Substances : Omega-3 Fatty Acids
Pharmacological Actions : Antidepressive Agents
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Psychopharmacol Neurosci. 2015 Aug 31 ;13(2):129-37. PMID: 26243838
Study Type : Review
Additional Links
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Immunomodulatory
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Pubmed Data : J Affect Disord. 2018 Oct 25. Epub 2018 Oct 25. PMID: 30391203
Study Type : Review
Additional Links
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : Med Hypotheses. 2014 May ;82(5):507-11. Epub 2014 Mar 3. PMID: 24630855
Study Type : Review
Additional Links
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : Med Hypotheses. 2014 Dec 30. Epub 2014 Dec 30. PMID: 25596911
Study Type : Commentary
Additional Links
Additional Keywords : Drug-Nutrient Depletion, Poor Diet
Problem Substances : Antidepressants
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Pubmed Data : CNS Neurol Disord Drug Targets. 2015 ;14(10):1312-4. PMID: 26556075
Study Type : Review
Additional Links
Diseases : Depression
Therapeutic Actions : Exercise
Additional Keywords : Microbiota
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Pubmed Data : Food Chem Toxicol. 2017 Oct ;108(Pt B):375-391. Epub 2016 Nov 24. PMID: 27890564
Study Type : Review
Additional Links
Substances : Perilla
Additional Keywords : Phytotherapy
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2015;2015:248529. Epub 2015 Jun 9. PMID: 26180581
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Rev. 2012 Jul ;6(12):81-90. PMID: 23055633
Study Type : Review
[+]
Pubmed Data : Nutr Neurosci. 2017 Jul 7:1-20. Epub 2017 Jul 7. PMID: 28686542
Study Type : Review
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Pubmed Data : Neurochem Res. 2013 Aug ;38(8):1624-31. Epub 2013 May 5. PMID: 23645163
Study Type : In Vitro Study
Additional Links
Substances : Bael
Diseases : Depression, Epilepsy
Pharmacological Actions : Anticonvulsants, Antidepressive Agents
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Pubmed Data : Am J Alzheimers Dis Other Demen. 2014 May ;29(3):205-14. Epub 2014 Jan 10. PMID: 24413543
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Psychiatry Clin Neurosci. 2019 Apr ;73(4):154-162. Epub 2019 Jan 6. PMID: 30499231
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Gut-brain Axis
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Pubmed Data : J Am Coll Nutr. 2015 ;34 Suppl 1:48-55. PMID: 26400435
Study Type : Review
Additional Links
Additional Keywords : Risk Reduction
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ther Adv Psychopharmacol. 2017 Jan ;7(1):54-56. Epub 2016 Oct 27. PMID: 28101325
Study Type : Review
Additional Links
Substances : Psilocybin
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : Psychiatry Res. 2015 Sep 30 ;229(1-2):27-36. Epub 2015 Jun 21. PMID: 26187338
Study Type : Review
Additional Links
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Psychopharmacol Neurosci. 2015 Dec 31 ;13(3):239-44. PMID: 26598580
Study Type : Review
Additional Links
Substances : Probiotics
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
Additional Keywords : Gut-brain Axis
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Aug 30 ;23(9). Epub 2018 Aug 30. PMID: 30200269
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Depression
Pharmacological Actions : Antioxidants
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Pubmed Data : ScientificWorldJournal. 2009;9:1233-41. Epub 2009 Nov 1. PMID: 19882093
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Neuritogenic
[+]
Pubmed Data : Annu Rev Nurs Res. 1999 ;17:57-84. PMID: 10418653
Study Type : Review
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2019 Apr 17 ;16(1):90. Epub 2019 Apr 17. PMID: 30995920
Study Type : Review
Additional Links
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Pubmed Data : J Clin Psychiatry. 2017 Jun ;78(6):e656-e667. PMID: 28682528
Study Type : Review
Additional Links
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : J Affect Disord. 2017 Nov 7 ;227:330-337. Epub 2017 Nov 7. PMID: 29136602
Study Type : Review
Additional Links
Substances : Saffron
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : J Complement Integr Med. 2018 May 30. Epub 2018 May 30. PMID: 29847314
Study Type : Review
Additional Links
Diseases : Depression
Therapeutic Actions : Yoga
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : Curr Neuropharmacol. 2016 ;14(2):165-76. PMID: 26903446
Study Type : Review
Additional Links
Substances : Salvia divinorum
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : Phytochemistry. 2017 Feb 10. Epub 2017 Feb 10. PMID: 28190678
Study Type : Review
Additional Links
Substances : Salvia divinorum
Pharmacological Actions : Antidepressive Agents, Antinoceceptive
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Pubmed Data : Psychiatry Res. 2005 Feb 28 ;133(2-3):197-203. PMID: 15740995
Study Type : Review
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
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Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2009 Feb 1;33(1):118-27. Epub 2008 Nov 12. PMID: 19028540
Study Type : Review
Additional Links
Substances : St. Johns Wort
Diseases : Depression
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Pubmed Data : J Cell Physiol. 2018 Nov 21. Epub 2018 Nov 21. PMID: 30461013
Study Type : Review
Additional Links
Substances : St. Johns Wort
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Natural Substances Versus Drugs
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Yoga. 2013 Jan ;6(1):4-10. PMID: 23440614
Study Type : Review
[+]
Pubmed Data : Psychoneuroendocrinology. 2016 Feb ;64:150-63. Epub 2015 Nov 25. PMID: 26677763
Study Type : Review
Additional Links
Diseases : Depression
Therapeutic Actions : Exercise, Meditation , Yoga
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Pubmed Data : J Ethnopharmacol. 2018 Mar 1 ;213:183-190. Epub 2017 Nov 21. PMID: 29166576
Study Type : Review
[+]
Pubmed Data : Mod Trends Pharmacopsychiatry. 2017 ;31:152-161. Epub 2017 Jul 24. PMID: 28738330
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Pubmed Data : Curr Opin Clin Nutr Metab Care. 2015 Nov ;18(6):552-8. PMID: 26372511
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Pubmed Data : Curr Top Behav Neurosci. 2018 ;36:137-158. PMID: 28677095
Study Type : Review
Additional Links
Diseases : Anxiety, Depression
Additional Keywords : Gene Expression Regulation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Gen Psychiatry. 2017 ;16:14. Epub 2017 Feb 20. PMID: 28239408
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : Gastroenterol Clin North Am. 2017 Mar ;46(1):77-89. Epub 2017 Jan 4. PMID: 28164854
Study Type : Review
Additional Links
Substances : Prebiotics, Probiotics
Diseases : Anxiety, Depression
Additional Keywords : Gut-brain Axis, Microbiome
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Psychol Bull. 2014 May ;140(3):774-815. Epub 2014 Jan 13. PMID: 24417575
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 Dec 2 ;17(12). Epub 2016 Dec 2. PMID: 27918465
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
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Pubmed Data : Neuropsychopharmacol Hung. 2016 Jun ;18(2):79-86. PMID: 27390204
Study Type : Review
Additional Links
Substances : Ayahuasca
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
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Pubmed Data : J Agric Food Chem. 2015 Aug 5. Epub 2015 Aug 5. PMID: 26244378
Study Type : Review
[+]
Pubmed Data : Brain Behav Immun. 2018 Jul 18. Epub 2018 Jul 18. PMID: 30009996
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Psychiatr Danub. 2018 Jun ;30(2):136-141. PMID: 29930222
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiota
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Psychiatry. 2018 ;9:205. Epub 2018 May 29. PMID: 29896124
Study Type : Review
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jun 6 ;10(6). Epub 2018 Jun 6. PMID: 29882776
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Psychiatry. 2018 ;9:669. Epub 2018 Dec 5. PMID: 30568608
Study Type : Review
Additional Links
Additional Keywords : Microbiome
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi Pharm J. 2018 Nov ;26(7):960-964. Epub 2018 Jun 8. PMID: 30416353
Study Type : In Vitro Study
Additional Links
Substances : Valerian
Diseases : Depression
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Pubmed Data : J Ethnopharmacol. 2019 Mar 1 ;231:241-252. Epub 2018 Nov 17. PMID: 30458281
Study Type : Review
[+]
Pubmed Data : Int Rev Psychiatry. 2018 Aug 13:1-14. Epub 2018 Aug 13. PMID: 30102082
Study Type : Review
Additional Links
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cureus. 2018 Aug 21 ;10(8):e3178. Epub 2018 Aug 21. PMID: 30357038
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Risk Factors
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Rev. 2013 Jul ;7(14):199-212. PMID: 24347928
Study Type : Review
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Pubmed Data : Annu Rev Neurosci. 2017 Mar 8. Epub 2017 Mar 8. PMID: 28301775
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiome, Microbiota
[+]
Pubmed Data : Neurochem Int. 2015 Nov ;90:224-31. Epub 2015 Sep 18. PMID: 26386393
Study Type : Review
[+]
Pubmed Data : J Anim Sci. 2017 Jul ;95(7):3225-3246. PMID: 28727115
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiota
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Pubmed Data : Am J Med Genet B Neuropsychiatr Genet. 2017 Sep ;174(6):651-660. Epub 2017 Jul 10. PMID: 28691768
Study Type : Review
Additional Links
Additional Keywords : Epigenetic Modification, Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:44. Epub 2016 Mar 4. PMID: 26973531
Study Type : Review
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dermatol Res Pract. 2015 ;2015:409637. Epub 2015 Oct 15. PMID: 26550011
Study Type : Review
Additional Links
Additional Keywords : Diseases that are Linked
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Trop Life Sci Res. 2016 Aug ;27(2):73-90. PMID: 27688852
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:519830. Epub 2015 Feb 19. PMID: 25789320
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2015 ;9:229. Epub 2015 Jul 3. PMID: 26190966
Study Type : Review
Additional Links
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Psychol. 2015 ;6:1093. Epub 2015 Aug 25. PMID: 26379564
Study Type : Review
[+]
Pubmed Data : Annu Rev Neurosci. 2016 Feb 24. Epub 2016 Feb 24. PMID: 27023732
Study Type : Review
Additional Links
Substances : Cannabidiol
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Pubmed Data : Prog Brain Res. 2018 ;242:69-96. Epub 2018 Aug 31. PMID: 30471683
Study Type : Review
Additional Links
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : J Agric Food Chem. 2015 Sep 16 ;63(36):7885-95. Epub 2015 Sep 1. PMID: 26306709
Study Type : Review
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Pubmed Data : Curr Med Chem. 2016 Apr 27. Epub 2016 Apr 27. PMID: 27121187
Study Type : Review
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants, Immunomodulatory
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Pubmed Data : Pharmacol Res. 2016 Feb 1. Epub 2016 Feb 1. PMID: 26845349
Study Type : Review
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rev Bras Psiquiatr. 2016 Mar ;38(1):65-72. PMID: 27111702
Study Type : Review
Additional Links
Substances : Ayahuasca
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]
Pubmed Data : Am J Psychiatry. 2015 Sep 11:appiajp201515020152. Epub 2015 Sep 11. PMID: 26357876
Study Type : Commentary
Additional Links
Additional Keywords : Microbiome
[+]
Pubmed Data : J Altern Complement Med. 2005 Aug ;11(4):711-7. PMID: 16131297
Study Type : Review
[+]
Pubmed Data : J Altern Complement Med. 2005 Feb ;11(1):189-201. PMID: 15750381
Study Type : Review
[+]
Pubmed Data : Eur Neuropsychopharmacol. 2004 Jan;14(1):7-10. PMID:14659982
Additional Links
Substances : St. Johns Wort

Depression Related Articles

Written by Pat Robinson
Kava is safe and effective in treating anxiety disorders and depression. L-tryptophan is as effective as imipramine in treating depression. Saffron may be of therapeutic benefit in the treatment of mild to moderate depression and has similar efficacy as the drug imipramine. St. John's Wort is as effective as Selective Serotoin Reuptake Inhibitors (SSRI) in the treatment of Depressive Disorder, with a greater safety rating.
What does the epidemic of depression and anxiety have to do with our obsession for dieting?

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