Depression research focused on Cannabidiol

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116 Substances Researched for Depression

Name	AC	CK
Vitamin D	8	90
Curcumin	14	84
St. John's Wort	5	60
Saffron	6	53
Omega-3 Fatty Acids	6	52
Homeopathic Medicine: All	5	50
DHA (Docosahexaenoic Acid)	3	40
EPA (Eicosapentaenoic Acid)	3	40
Lavender	4	40
Ayahuasca	7	34
Psilocybin	5	32
Rhodiola (Tibetan Ginseng)	4	32
Polyunsaturated Fatty Acids (PUFAs)	3	31
Kava Kava	2	30
Magnesium	3	30
SAMe (S-adenosylmethionine)	2	30
Tryptophan	3	30
Probiotics	5	24
Ginkgo biloba	2	21
Acetyl-l-carnitine	2	20
Bergamot	2	20
Chlorella (Algae)	2	20
Coffee	2	20
Docosahexaenoic acid (DHA)	1	20
Eicosapentaenoic acid (EPA)	1	20
Fruit: All	1	20
Lavender: Essential Oil	1	20
Soy	2	20
Vegetables: All	1	20
Rosemary	4	16
Cocoa	2	11
Lion's Mane (Hericium Erinaceus)	2	11
5-HTP (5-Hydroxytryptophan)	1	10
Blue-Green Algae	1	10
Chamomile	1	10
Coenzyme Q10	1	10
DHEA (Dehydroepiandrosterone)	1	10
Essential Fatty Acids	1	10
Eucalyptus	1	10
Fish	1	10
Frankincense	1	10
Goji	1	10
Marjoram	1	10
Motherwort	1	10
Niacin	1	10
Piperidines	1	10
Selenium	1	10
Vitamin E	1	10
Zinc	1	10
Cannabidiol	5	8
Piperine	4	8
Melatonin	4	6
Bacopa	3	5
Polyphenols	4	5
Resveratrol	3	5
Gardenia	2	4
Fiber	1	3
Flavonoids	2	3
Green Tea	2	3
Lysergic Acid Diethylamide (LSD)	3	3
Salvia divinorum	2	3
Apigenin	1	2
Ashwagandha	1	2
Asparagus	1	2
Astaxanthin	1	2
Bamboo	1	2
Berberine	1	2
Bifidobacterium Infantis	1	2
Bifidobacterium Longum	1	2
Bitter Orange	1	2
Black Pepper	1	2
Cannabinoids	1	2
Cannabis	1	2
Catuaba	1	2
Chokeberry	1	2
Dandelion	1	2
Delta-tetrahydrocannabinol (THC)	1	2
Dill	1	2
Feijoa	1	2
Fenugreek	1	2
Fisetin	1	2
Flaxseed	1	2
Geraniol	1	2
Kratom	2	2
Krill	1	2
Lactobacillus rhamnosus	1	2
Lettuce	1	2
Lobelia	1	2
Luteolin	1	2
Magnolia	1	2
Mango	1	2
Moringa oleifera	1	2
Mucuna pruriens (aka Velvet Beans)	1	2
Musk (Animal)	1	2
Myricetin	1	2
Nutmeg	1	2
Onion	1	2
Panax Ginseng	1	2
Perilla	1	2
Pycnogenol (Pine Bark)	1	2
Sesamol	1	2
Silibinin	1	2
Sulforaphane	1	2
Thistle	1	2
Tualang Honey	1	2
Valerian	1	2
ALA (Alpha-Linolenic Acid)	1	1
Anthocyanins	1	1
Catechin	1	1
Chrysin	1	1
Curcumin: Degradiation byproducts	1	1
Folic Acid	1	1
Graviola	1	1
Oak	1	1
Prebiotics	1	1
St. Johns Wort	2	1

24 Problem Substances Researched for Depression

Name	AC	CK
Fluoxetine (trade name Prozac)	14	132
Antidepressants	6	61
Sertraline	5	34
Selective Serotonin Reuptake Inhibitors (SSRIs)	3	22
Chemotherapy	1	20
Eszopiclone	1	20
Hypnotic Drugs	1	20
Ramelteon	1	20
Statin Drugs	2	20
Zaleplon	1	20
Zolpidem (trade name Ambien)	1	20
Bisphenol A	2	11
Simvastatin	2	11
Analgesic: Non-opioid	1	10
Fenofibrates	1	10
Fried Foods	1	10
Gliadin	1	10
Hydrocarbons	1	10
Nicotine	1	10
Phthalates	1	10
Sugar Sweetened Beverages	1	10
Tobacco: Smoking	1	10
Paroxetine (trade names Seroxat, Paxil)	1	3
Monosodium Glutamate (MSG)	1	2

39 Therapeutic Actions Researched for Depression

Name	AC	CK
Acupuncture	10	100
Integrative Medicine	6	70
Yoga	9	63
Massage/Therapeutic Touch	3	40
Exercise	3	31
Shinrin-yoku (taking in the atmosphere of the forest)	4	31
Emotional Freedom Technique	3	30
Horticultural Therapy (Gardening)	3	30
Light Therapy	3	30
Meditation	2	30
Mindfullness Training	3	30
Yogic Technique: Sudarshan kriya	5	23
Exercise: Green	3	21
Aromatherapy	2	20
Electroacupuncture	2	20
Exercise: Aerobic	2	20
Music	1	20
Placebo Effect	2	20
Acupressure	1	10
Acupressure: Auricular	1	10
Aromatherapy Massage	1	10
Behavioral Treatment	1	10
Cognitive Behavioural Approaches	1	10
Color Therapy	1	10
Dancing	1	10
Dietary Modification: Mediterranean Diet	1	10
Homeopathic Treatment	1	10
Hormone Replacement Therapy	1	10
Hydrotherapy	1	10
Hypnosis	1	10
Laughter/Humor	1	10
Positive Mood	1	10
Prevent Pain	1	10
Qigong	1	10
Reiki Therapy	1	10
Sauna Therapy	1	10
Sunlight exposure	1	10
Therapeutic Breathing	1	10
Guided Imagery	1	1

8 Problematic Actions Researched for Depression

Name	AC	CK
Chemotherapy	1	20
Angioplasty	1	10
Electromagnetic Fields	1	10
Nocebo Effect	1	10
Western Diet	1	10
X-ray Mammography	1	10
Prenatal Stress	1	2
Stress	1	2

Focused Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD

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View the Evidence:
10 Abstracts with Depression
& Cannabidiol Research

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Antidepressant-like effect induced by cannabidiol is dependent on brain serotonin levels.Jun 05, 2018

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Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 6. Epub 2018 Jun 6. PMID: 29885468

Article Published Date : Jun 05, 2018

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Cannabidiol could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate cortical signalling.Dec 18, 2015

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Pubmed Data : Neuropharmacology. 2015 Dec 19. Epub 2015 Dec 19. PMID: 26711860

Article Published Date : Dec 18, 2015

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Cannabidiol regulates the expression of hypothalamus-pituitary-adrenal axis-related genes in response to acute restraint stress.Oct 15, 2018

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Pubmed Data : J Psychopharmacol. 2018 Oct 16:269881118805495. Epub 2018 Oct 16. PMID: 30324842

Article Published Date : Oct 15, 2018

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Anxiety, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

CBD induces antidepressant-like effects comparable to those of imipramine. Dec 31, 2009

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Pharmacol. 2010 Jan ;159(1):122-8. Epub 2009 Dec 4. PMID: 20002102

Article Published Date : Dec 31, 2009

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

CBD may be beneficial for the treatment of clinical depression and other states with prominent anhedonia.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Neuropsychobiology. 2016 ;73(2):123-9. Epub 2016 Mar 25. PMID: 27010632

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Delta-tetrahydrocannabinol, cannabidiol, and cannabichromene exert antidepressant-like actions in animal models.May 31, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmacol Biochem Behav. 2010 Jun ;95(4):434-42. Epub 2010 Mar 21. PMID: 20332000

Article Published Date : May 31, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabinoids , Cannabis, Delta-tetrahydrocannabinol (THC)

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Effects of cannabidiol in males and females in two different rat models of depression.Dec 16, 2018

Click here to read the entire abstract

Pubmed Data : Physiol Behav. 2018 Dec 17. Epub 2018 Dec 17. PMID: 30571957

Article Published Date : Dec 16, 2018

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Cannabis and the cannabinoids in addition to their potential applications in the treatment of a number of serious illnesses.Dec 31, 2016

Click here to read the entire abstract

Pubmed Data : Prog Chem Org Nat Prod. 2017;103:1-36. PMID: 28120229

Article Published Date : Dec 31, 2016

Study Type : Review

Additional Links

Substances : Cannabichromene , Cannabidiol, Cannabigerol , Cannabinoids , Cannabis

Diseases : Alzheimer's Disease, Cancers: All, Depression, Glaucoma, HIV Infections, Multiple Sclerosis, Neuralgia

[+]

This reviews preclinical and clinical on the efficacy of CBD for the treatment of motivational disorders.Feb 23, 2016

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Pubmed Data : Annu Rev Neurosci. 2016 Feb 24. Epub 2016 Feb 24. PMID: 27023732

Article Published Date : Feb 23, 2016

Study Type : Review

Additional Links

Substances : Cannabidiol

Diseases : Anxiety Disorders, Depression, Drug Abuse

[+]

This summarizes the therapeutic effects of CBD and their relevance to brain function, neuroprotection and neuropsychiatric disorders.Jan 31, 2016

Click here to read the entire abstract

Pubmed Data : Pharmacol Res. 2016 Feb 1. Epub 2016 Feb 1. PMID: 26845349

Article Published Date : Jan 31, 2016

Study Type : Review

Additional Links

Substances : Cannabidiol

Diseases : Anxiety Disorders, Brain Damage, Brain Ischemia, Depression, Neurodegenerative Diseases, Psychiatric Disorders

Pharmacological Actions : Neuroprotective Agents

Depression Related Articles

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Written by Margie King, Health Coach

What does the epidemic of depression and anxiety have to do with our obsession for dieting?

23 Natural Alternatives for Depression

Written by Pat Robinson

Kava is safe and effective in treating anxiety disorders and depression. L-tryptophan is as effective as imipramine in treating depression. Saffron may be of therapeutic benefit in the treatment of mild to moderate depression and has similar efficacy as the drug imipramine. St. John's Wort is as effective as Selective Serotoin Reuptake Inhibitors (SSRI) in the treatment of Depressive Disorder, with a greater safety rating.

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Focus Your Research

Click any topic below to filter + focus research

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View the Evidence: 10 Abstracts with Depression & Cannabidiol Research

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Currently Available Sorting Options

Antidepressant-like effect induced by cannabidiol is dependent on brain serotonin levels.Jun 05, 2018

Cannabidiol could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate cortical signalling.Dec 18, 2015

Cannabidiol regulates the expression of hypothalamus-pituitary-adrenal axis-related genes in response to acute restraint stress.Oct 15, 2018

CBD induces antidepressant-like effects comparable to those of imipramine. Dec 31, 2009

CBD may be beneficial for the treatment of clinical depression and other states with prominent anhedonia.Dec 31, 2015

Delta-tetrahydrocannabinol, cannabidiol, and cannabichromene exert antidepressant-like actions in animal models.May 31, 2010

Effects of cannabidiol in males and females in two different rat models of depression.Dec 16, 2018

Cannabis and the cannabinoids in addition to their potential applications in the treatment of a number of serious illnesses.Dec 31, 2016

This reviews preclinical and clinical on the efficacy of CBD for the treatment of motivational disorders.Feb 23, 2016

This summarizes the therapeutic effects of CBD and their relevance to brain function, neuroprotection and neuropsychiatric disorders.Jan 31, 2016

Depression Related Articles

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Depression research focused on Cannabidiol

View the Evidence:
10 Abstracts with Depression
& Cannabidiol Research