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Depression: 21st Century Solutions + The Dark Side of Wheat

Article Publish Status: FREE
Abstract Title:

Antinociceptive activity of Mentha piperita leaf aqueous extract in mice.

Abstract Source:

Libyan J Med. 2012 ;7. Epub 2012 Mar 27. PMID: 22468149

Abstract Author(s):

Yousef A Taher

Article Affiliation:

Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Tripoli University, Tripoli, Libya.

Abstract:

BACKGROUND: Mentha piperita L. (Labiatae) is an herbaceous plant, used in folk medicine for the treatment of several medical disorders.

METHODS AND RESULTS: In the present study, the aqueous extract of Mentha piperita leaf, at the i.p doses 200 and 400 mg/kg, showed significant analgesic effects against both acetic acid-induced writhing and hot plate-induced thermal stimulation in mice, with protection values of 51.79% and 20.21% respectively. On the contrary, the Mentha piperita leaf aqueous extract did not exhibit anti-inflammatory activity against carrageenan induced paw oedema.

CONCLUSION: These findings indicate that Mentha piperita has a potential analgesic effect that may possibly have mediated centrally and peripherally, as well as providing a pharmacological evidence for its traditional use as a pain reliever.

Study Type : Animal Study
Additional Links
Pharmacological Actions : Analgesics : CK(1327) : AC(217)

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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