Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get two FREE E-Books

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Depression: 21st Century Solutions + The Dark Side of Wheat

n/a
Abstract Title:

Walnut (Juglans regia L.) kernel extracts protects against isoproterenol-induced myocardial infarction in rats.

Abstract Source:

Rejuvenation Res. 2018 Nov 6. Epub 2018 Nov 6. PMID: 30398390

Abstract Author(s):

Ya Sun, Guangzhao Qi, Duolu Li, Haiyang Meng, Zhenfeng Zhu, Yongmei Zhao, Yuedong Qi, Xiaojian Zhang

Article Affiliation:

Ya Sun

Abstract:

Walnuts kernels (Juglans regia L.) have rich antioxidants content and have been used in both cosmetic and pharmaceutical industry. The current study dealt with the protective role of walnut kernels extracts (WK) on isoproterenol (ISO)-induced myocardial infarction (MI) in rats. Rats were pretreated with WK extracts (300 mg/kg) daily for 35 days. Then, isoproterenol (100 mg/kg) was injected subcutaneously into rats to induce myocardial infarction. Cardiac diagnostic markers (LDH and CPK), cardiac troponin, heart lipid peroxidation (TBARS and hydroperoxide), antioxidant system (CAT, SOD, GPx, GST, GSH and GSSG) and the levels of lipid profile were evaluated in rats, and the results revealed WK significantly prevented myocardial injury induced by ISO (P<0.05). WK significantly alleviated the oxidative damage and dyslipidemia in isoproterenol-induced MI rats (P<0.05). The effect produced by WK was compared withα-tocopherol. The mechanisms for the protective effects of WK could be attributed to its antilipid peroxidative, antioxidant and antilipidaemic properties. In conclusion, we demonstrated that WK has a significant protective effect against ISO-induced myocardial infarction.

Study Type : Animal Study

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get two FREE E-Books

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Depression: 21st Century Solutions + The Dark Side of Wheat

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2018 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.