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Depression: 21st Century Solutions + The Dark Side of Wheat

Abstract Title:

Vitamin D deficiency and depression among women from an urban community in a tropical country.

Abstract Source:

Public Health Nutr. 2016 Apr 18:1-7. Epub 2016 Apr 18. PMID: 27086558

Abstract Author(s):

Foong Ming Moy, Victor Cw Hoe, Noran Naqiah Hairi, Shireene Ratna Vethakkan, Awang Bulgiba

Article Affiliation:

Foong Ming Moy

Abstract:

OBJECTIVE: To determine the association of vitamin D status with depression and health-related quality of life among women.

DESIGN: This was a cross-sectional study conducted among women in Kuala Lumpur, Malaysia. Sociodemographic characteristics, physical activity status, perceived depression and health-related quality of life were assessed via a self-administered questionnaire. Fasting blood samples were taken for the analysis of 25-hydroxyvitamin D, parathyroid hormone, fasting blood glucose and full lipid profile. Complex samples multiple logistic regression analysis was performed.

SETTING: Public secondary schools in Kuala Lumpur, Malaysia.

SUBJECTS: Seven hundred and seventy female teachers were included.

RESULTS: The mean age of participants was 41·15 (95 % CI 40·51, 41·78) years and the majority were ethnic Malays. Over 70 % of them had vitamin D deficiency (<20 ng/ml or<50 nmol/l) and two-thirds were at risk for depression. In the multivariate analysis, ethnic Malays (adjusted OR (aOR)=14·72; 95 % CI 2·12, 102·21) and Indians (aOR=14·02; 95 % CI 2·27, 86·59), those at risk for depression (aOR=1·88, 95 % CI 1·27, 2·79) and those with higher parathyroid hormone level (aOR=1·13; 95 % CI 1·01, 1·26) were associated with vitamin D deficiency, while vitamin D deficiency was negatively associated with mental health-related quality of life (Mental Component Summary) scores (aOR=0·98; 95 % CI 0·97, 0·99).

CONCLUSIONS: Vitamin D deficiency is significantly associated with depression and mental health-related quality of life among women in Kuala Lumpur, Malaysia.

Study Type : Human Study

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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