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Article Publish Status: FREE
Abstract Title:

The Antibacterial Effectof Honey Derived from Various Danish Flora.

Abstract Source:

Dermatol Res Pract. 2018 ;2018:7021713. Epub 2018 Jun 19. PMID: 30018636

Abstract Author(s):

Reem Dina Matzen, Julie Zinck Leth-Espensen, Therese Jansson, Dennis Sandris Nielsen, Marianne N Lund, Steen Matzen

Article Affiliation:

Reem Dina Matzen

Abstract:

The mechanism behind the biologic actions of honey as a wound remedy has been intensively studied; however, there is no published data regarding any antibacterial effect of honey derived from Danish flora. We surveyed 11 honeys of various Danish floral sources for their antibacterial activity and compared them to a culinary processed commercial honey (Jakobsens) and a raw and a medical grade Manuka () honey using the agar-well diffusion method. We tested the effect on three gram-positive bacteria (two strains ofand one strain of) and two gram-negative bacteria (and). All samples, except the commercial honey, exhibited antibacterial activity, and samples derived from Water Mint (Organic 2 (mixed organic flora), and Linden () honey had consistent effects on all bacteria tested and showed greater effect than medical grade and raw Manuka () honey. The content of methylglyoxal was low in the Danish honey (<2 g/mL) and significantly (p<0.05) higher in both the raw and the medical grade Manuka () honey, where the concentrations were, respectively, 6.29 g/mL and 54.33 g/mL. The antibacterial effect of Danish honeys was mostly due to hydrogen peroxide. We conclude that honeys derived from Danish flora possess antibacterial effect, probably by a hurdle effect of viscosity, osmolality, acidity, bioactive peptides, and most importantly the content of hydrogen peroxide. These findings indicate that honeys of various Danish floral sources may have clinical potential, although further studies are necessary to elucidate this in order to determine whether the results of ourexperiments also apply to a clinical setting.

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Depression: 21st Century Solutions + The Dark Side of Wheat

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