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Depression: 21st Century Solutions + The Dark Side of Wheat

Abstract Title:

[The some risk factors for atherosclerosis in men with coronary artery disease depending on the age].

Abstract Source:

Pol Merkur Lekarski. 2007 Jul;23(133):9-14. PMID: 18051823

Abstract Author(s):

Elwira Stasiakowska-Badura, Marek Kochmański

Article Affiliation:

Central Clinical Hospital of Ministry of Interior and Administration, Warsaw, Poland. jolanta.seroczynska@CSKMSWIA.pl

Abstract:

The aim of this study was to search to the factors favouring the earlier revealing of a coronary artery disease by comparing selected immunological, hormonal and biochemical parameters between two groups--younger and older men with coronary artery disease and with responding control groups. MATERIAL AND METHODS: In the study were included 93 men--60 with stable angina, confirmed by coronarography (at least 6 months after CABG, PTCA or myocardial infraction, with EF>40%) and 33 men without atherosclerotic changes in the coronary vessels, as the control group. The two groups were divided depending on age: the younger subgroups [under 60-ty years old--group A with CAD (n=30) and B without CAD (n=18)] and the older subgroup [over 70-ty years old group C with CAD (n=30) and D without CAD (n=15)]. RESULTS: Significantly lower concentration were noted for TNF-alpha--in control groups--by about 50% in the younger and 23% in the older group (r = 0.49) and homocysteine (by about 20% and 22% respectively, r = 0.40). Patients with CAD had higher concentration of CRP then in the control groups (by 52% and 54%, r = 0.28). Weak but positive correlation with the presence of a coronary heart disease was show for IgE and anti-gliadin antibodies (r = 0. 22-0.29). CONCLUSION: The younger and older men with CAD statistically significantly differed in concentration of TNF-alpha and homocysteine.

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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