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Abstract Title:

Anti-inflammatory and antioxidant activities of extracts from Musa sapientum peel.

Abstract Source:

J Med Assoc Thai. 2012 Jan ;95 Suppl 1:S142-6. PMID: 23964457

Abstract Author(s):

Pathompong Phuaklee, Srisopa Ruangnoo, Arunporn Itharat

Article Affiliation:

Pathompong Phuaklee

Abstract:

BACKGROUND: Many parts of Musa sapientum Linn. (Musaceae) are used in Thai traditional medicine as drugs, food supplements and cosmetics. The banana peel is used as an astringent in foot care, the unripe fruit is used to treat diarrhea and, the ripe fruit is used as tonic.

OBJECTIVE: To evaluate anti-inflammatory and antioxidant activities of banana peel extracts obtained from different extraction methods and to determine their total phenolic content.

MATERIAL AND METHOD: Four extraction methods were used to extract unripe and ripe peels. Nitric oxide inhibitory and DPPH scavenging assays were used to evaluate anti-inflammatory and antioxidant activities, respectively. Folin-Ciocalteu's reagent was used to determine total phenolic content.

RESULTS: The water extract of fresh ripe peel exhibited the most potent NO inhibitory activity (IC50 = 6.68 +/- 0.34 microg/ml), but apparently exhibited no antioxidant activity. The decoction extract of fresh unripe peel exhibited strong antioxidant activity as well as had the highest total phenolic compound. The antioxidant activity exhibited a correlation with the total phenolic content.

CONCLUSION: This study supports the use of Musa sapientum peel in Thai Traditional Medicine for treatment of inflammatory-related diseases.

Study Type : In Vitro Study

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Sayer Ji
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