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Depression: 21st Century Solutions + The Dark Side of Wheat

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Article Publish Status: FREE
Abstract Title:

Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects.

Abstract Source:

Evid Based Complement Alternat Med. 2018 ;2018:1709182. Epub 2018 Jan 17. PMID: 29576792

Abstract Author(s):

Nadia Gulluni, Tania Re, Idalba Loiacono, Giovanni Lanzo, Luigi Gori, Claudio Macchi, Francesco Epifani, Nicola Bragazzi, Fabio Firenzuoli

Article Affiliation:

Nadia Gulluni

Abstract:

We examined the effects of essential oil from legal (THC<0.2% w/v) hemp variety on the nervous system in 5 healthy volunteers. GC/EIMS and GC/FID analysis of the EO showed that the main components were myrcene and-caryophyllene. The experiment consisted of measuring autonomic nervous system (ANS) parameters; evaluations of the mood state; and electroencephalography (EEG) recording before treatment, during treatment, and after hemp inhalation periods as compared with control conditions. The results revealed decreased diastolic blood pressure, increased heart rate, and significant increased skin temperature. The subjects described themselves as more energetic, relaxed, and calm. The analysis EEG showed a significant increase in the mean frequency of alpha (8-13 Hz) and significant decreased mean frequency and relative power of beta 2 (18,5-30 Hz) waves. Moreover, an increased power, relative power, and amplitude of theta (4-8 Hz) and alpha brain waves activities and an increment in the delta wave (0,5-4 Hz) power and relative power was recorded inthe posterior region of the brain. These results suggest that the brain wave activity and ANS are affected by the inhalation of the EO ofsuggesting a neuromodular activity in cases of stress, depression, and anxiety.

Study Type : Human Study

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Depression: 21st Century Solutions + The Dark Side of Wheat

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