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Depression: 21st Century Solutions + The Dark Side of Wheat

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Article Publish Status: FREE
Abstract Title:

Intervention strategies for cesarean section-induced alterations in the microbiota-gut-brain axis.

Abstract Source:

Nutr Rev. 2017 Apr 1. Epub 2017 Apr 1. PMID: 28379454

Abstract Author(s):

Angela Moya-Pérez, Pauline Luczynski, Ingrid B Renes, Shugui Wang, Yuliya Borre, C Anthony Ryan, Jan Knol, Catherine Stanton, Timothy G Dinan, John F Cryan

Article Affiliation:

Angela Moya-Pérez

Abstract:

Microbial colonization of the gastrointestinal tract is an essential process that modulates host physiology and immunity. Recently, researchers have begun to understand how and when these microorganisms colonize the gut and the early-life factors that impact their natural ecological establishment. The vertical transmission of maternal microbes to the offspring is a critical factor for host immune and metabolic development. Increasing evidence also points to a role in the wiring of the gut-brain axis. This process may be altered by various factors such as mode of delivery, gestational age at birth, the use of antibiotics in early life, infant feeding, and hygiene practices. In fact, these early exposures that impact the intestinal microbiota have been associated with the development of diseases such as obesity, type 1 diabetes, asthma, allergies, and even neurodevelopmental disorders. The present review summarizes the impact of cesarean birth on the gut microbiome and the health status of the developing infant and discusses possible preventative and restorative strategies to compensate for early-life microbial perturbations.

Study Type : Review
Additional Links
Additional Keywords : Microbiome : CK(121) : AC(24)
Anti Therapeutic Actions : Cesarean Delivery : CK(686) : AC(51)

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Depression: 21st Century Solutions + The Dark Side of Wheat

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