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Abstract Title:

Levothyroxine Medication is Associated with Adiposity Independent of TSH.

Abstract Source:

Exp Clin Endocrinol Diabetes. 2012 May 25. Epub 2012 May 25. PMID: 22639395

Abstract Author(s):

S Ruhla, A M Arafat, M Osterhoff, M O Weickert, K Mai, J Spranger, C Schöfl, A F H Pfeiffer, M Möhlig

Article Affiliation:

Department of Endocrinology, Diabetes and Nutrition, Charité-University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany.

Abstract:

In euthyroidism, higher TSH levels are weakly associated with increased BMI. Furthermore, a considerable number of patients complain of weight gain during thyroid hormone replacement after thyroidectomy. We therefore investigated the association between levothyroxine medication and BMI in a large cross-sectional study group.We included euthyroid participants from the MeSyBePo study group (TSH between 0.3 and 4.5μU/ml) that did not take thyreostatic drugs. Linear regression analyses were performed to address the association between levothyroxine medication and obesity. Additionally, pairs matched by sex, age and TSH but discordant in levothyroxine medication were compared.1 663 subjects (569 males) were eligible for inclusion. 151 participants were taking levothyroxine. Adjusted for sex and age both TSH (standardised beta 0.1, p<0.001) and levothyroxine medication (standardised beta 0.05, p=0.03) were significantly associated with BMI. There was no significant interaction between TSH and levothyroxine medication with respect to BMI. Further adjustment for smoking and the restriction to those subjects with normal glucose metabolism (947 participants (314 males, 82 on levothyroxine medication) did not alter the result. In matched pair analysis (133 pairs), BMI was significantly increased in subjects taking levothyroxine compared to controls.Independently from TSH, levothyroxine medication was associated with a higher BMI. The mechanisms, however, responsible for this association need to be elucidated.

Study Type : Human Study
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iodine, iodine, iodine



I avoided levothroxine by taking a different path.  Vegan diet.  Prolamine Iodine by Standard Process every day, Cayce's castor oil therapy over the liver every night for 2 weeks, Unfiltered apple cider vinegar every day and an alkaline diet to keep an alkaline pH.  Finally, I had my chakras balanced every week for 3 months.  At the end of the time, I went back to the doctor who told me he had clearly got the dosage right and was shocked when I told him I hadn't taken a single pill.  For the past 3 years I have had thyroid tests every six months and everything is perfectly normal.  This might not be an approach for many but it worked for me.  I still continue these treatment protocols except for the Edgar Cayce castor oil patches and the vegan diet.  Every few months though, I do a vegan stint for a couple of months.

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Sayer Ji
Founder of GreenMedInfo.com

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Easy Turmeric recipes + The Dark Side of Wheat

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