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Depression: 21st Century Solutions + The Dark Side of Wheat

Abstract Title:

Hyperamylasemia due to macroamylasemia in adult gluten enteropathy.

Abstract Source:

Scand J Clin Lab Invest. 1997 May ;57(3):271-3. PMID: 9238763

Abstract Author(s):

G Bonetti, G Serricchio, A Giudici, M Bettonagli, G B Vadacca, R Bruno, E Coslovich, R Moratti

Article Affiliation:

Department of Clinical Biochemistry, University of Pavia, Policlinico San Matteo, Italy.

Abstract:

We report hyperamylasemia due to macroamylasemia in a 33-year-old-woman with gluten enteropathy. Macroamylasemia was demonstrated by precipitation of 97% of amylase activity with PEG 6000. It was associated with increased serum IgA, with elevated values of specific IgA antibodies against alpha-gliadin and with a high titre of IgA anti-endomysium antibodies. Macroamylasemia disappeared after 2 months of a strict gluten-free diet. These data suggest that the increased IgA concentration in adult gluten enteropathy led to increased macroamylase formation.

Study Type : Human: Case Report

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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