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Depression: 21st Century Solutions + The Dark Side of Wheat

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Article Publish Status: FREE
Abstract Title:

Increased Mercury Levels in Patients with Celiac Disease following a Gluten-Free Regimen.

Abstract Source:

Gastroenterol Res Pract. 2015 ;2015:953042. Epub 2015 Feb 23. PMID: 25802516

Abstract Author(s):

Luca Elli, Valentina Rossi, Dario Conte, Anna Ronchi, Carolina Tomba, Manuela Passoni, Maria Teresa Bardella, Leda Roncoroni, Gianpaolo Guzzi

Article Affiliation:

Luca Elli

Abstract:

Background and Aim. Although mercury is involved in several immunological diseases, nothing is known about its implication in celiac disease. Our aim was to evaluate blood and urinary levels of mercury in celiac patients. Methods. We prospectively enrolled 30 celiac patients (20 treated with normal duodenal mucosa and 10 untreated with duodenal atrophy) and 20 healthy controls from the same geographic area. Blood and urinary mercury concentrations were measured by means of flow injection inductively coupled plasma mass spectrometry. Enrolled patients underwent dental chart for amalgam fillings and completed a food-frequency questionnaire to evaluate diet and fish intake. Results. Mercury blood/urinary levels were 2.4± 2.3/1.0 ± 1.4, 10.2 ± 6.7/2.2 ± 3.0 and 3.7 ± 2.7/1.3 ± 1.2 in untreated CD, treated CD, and healthy controls, respectively. Resulting mercury levels were significantly higher in celiac patients following a gluten-free diet. No differences were found regarding fish intake and number of amalgam fillings. No demographic or clinical data were significantly associated with mercury levels in biologic samples. Conclusion. Data demonstrate a fourfold increase of mercury blood levels in celiac patients following a gluten-free diet. Further studies are needed to clarify its role in celiac mechanism.

Study Type : Human Study
Additional Links
Problem Substances : Mercury : CK(237) : AC(38)

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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