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Depression: 21st Century Solutions + The Dark Side of Wheat

Article Publish Status: FREE
Abstract Title:

Impact of daily supplementation of Spirulina platensis on the immune system of naïve HIV-1 patients in Cameroon: a 12-months single blind, randomized, multicenter trial.

Abstract Source:

Nutr J. 2015 ;14:70. Epub 2015 Jul 21. PMID: 26195001

Abstract Author(s):

Marthe-Elise Ngo-Matip, Constant Anatole Pieme, Marcel Azabji-Kenfack, Bruno Moukette Moukette, Emmanuel Korosky, Philippe Stefanini, Jeanne Yonkeu Ngogang, Carl Moses Mbofung

Article Affiliation:

Marthe-Elise Ngo-Matip

Abstract:

BACKGROUND: Micronutrient deficiencies occur early in Human Immunodeficiency Virus (HIV) infections they have reverse effects on the nutritional status. The diet supplementation with a natural nutraceutical rich in proteins and micronutrient like Spirulina platensis, may be effective and efficient in delaying HIV disease progression by frequently reported improvement in immune response.

METHODS: A prospective single-blind, randomized, multicenter study conducted on 320 HIV-1 ARV-naïve participants for 12 months. Participants received either S. platensis supplementation and standard care or standard care and local balanced diet without S. platenis. Selected hematological and biochemical as well as CD4 count cells, viral load copies were assessed at three separate times.

RESULTS: Among the 169 ART-naïve participants enrolled in the study, the female was mostly represented (67.1%). The significant increase of CD4 count cells (596.32-614.92 cells count) and significant decrease of viral load levels (74.7 × 10(3)-30.87 × 10(3) copies/mL) of the patients who received a supplementation ofS. platensis was found after 6 months of treatment. Haemoglobin level was also significantly higher in the same group while the fasting blood glucose concentration decreased after 12 months compared to control.

CONCLUSION: A daily supplementation with S. platensis to diet combined with a reasonable balanced diet has significantly increased the CD4 cells and reduced the viral load after 6 months. Further studies are recommended among a large specific group of people infected by the HIV in order to investigate the mechanisms involved on the effect of S. platensis on immune system.

Study Type : Human Study
Additional Links
Pharmacological Actions : Immunomodulatory : CK(1287) : AC(358)

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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