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Depression: 21st Century Solutions + The Dark Side of Wheat

Abstract Title:

Collagenous enterocolitis: a manifestation of gluten-sensitive enteropathy.

Abstract Source:

J Clin Gastroenterol. 1992 Jul ;15(1):45-51. PMID: 1500661

Abstract Author(s):

T M McCashland, J P Donovan, R S Strobach, J Linder, E M Quigley

Article Affiliation:

Department of Internal Medicine, University of Nebraska Medical Center, Omaha 68198-2000.

Abstract:

We report coexistent collagenous colitis and collagenous sprue in a 62-year-old woman with diarrhea. Investigations suggested malabsorption, and small intestinal biopsies demonstrated a flattened mucosa with subepithelial collagen deposition. Colonic biopsies also showed a thickened subepithelial collagen band as well as a striking lamina propria inflammatory cell infiltrate. Symptomatic remission was induced with a gluten/lactose-free diet, oral prednisone, and sulfasalazine and has been maintained with gluten restriction alone. Repeat biopsies after 2 months demonstrated restoration of normal small intestinal and colonic collagen bands; only a chronic inflammatory cell infiltrate (consistent with microscopic/lymphocytic colitis) persisted in colonic biopsies. We propose that, in this instance, collagenous enterocolitis represented a diffuse manifestation of gluten sensitivity.

Study Type : Human Study

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Sayer Ji
Founder of GreenMedInfo.com

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Depression: 21st Century Solutions + The Dark Side of Wheat

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