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Depression: 21st Century Solutions + The Dark Side of Wheat

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Article Publish Status: FREE
Abstract Title:

Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus.

Abstract Source:

Asia Pac J Clin Nutr. 2018 ;27(2):341-346. PMID: 29384321

Abstract Author(s):

Nafiseh Sokri Mashhadi, Mehrnoosh Zakerkish, Javad Mohammadiasl, Mehdi Zarei, Majid Mohammadshahi, Mohammad Hossein Haghighizadeh

Article Affiliation:

Nafiseh Sokri Mashhadi

Abstract:

BACKGROUND AND OBJECTIVES: This randomized, placebo-controlled trial was performed for 8 weeks to investigate the potential effects of astaxanthin (AST) supplementation on the adiponectin concentration, lipid peroxidation, glycemic control, insulin sensitivity, and anthropometric indices in participants with type 2 diabetes mellitus.

METHODS AND STUDY DESIGN: We enrolled 44 participants with type 2 diabetes who met our inclusion criteria. Eight milligrams of AST supplementation or a placebo were randomly administered once daily for 8 weeks to these participants.

RESULTS: The 8-week administration of AST supplementation increased the serum adiponectin concentration and reduced visceral body fat mass (p<0.01), serum triglyceride and very-low-density lipoprotein cholesterol concentrations, and systolic blood pressure (p<0.05). Furthermore, AST significantly reduced the fructosamine concentration (p<0.05) and marginally reduced the plasma glucose concentration (p=0.057).

CONCLUSIONS: We demonstrated that because participants with type 2 diabetes often have hypertriglycemia and uncontrolled glucose metabolism; our findings of dual beneficial effects are clinically valuable. Our results may provide a novel complementary treatment with potential impacts on diabetic complications without adverse effects.

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Depression: 21st Century Solutions + The Dark Side of Wheat

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